WormBase Tree Display for RNAi: WBRNAi00092474
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WBRNAi00092474 | Homol | Homol_homol | K07C11:RNAi | |
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Sequence_info | DNA_text | ATGAGCGGAAAGGAAAATACTGCTCCTGTGATAGACGATCAGAAGGCCGAGGTTATTTCACTTACGGAAGATAGCAGACCTCAGAGAGTTGACCAGGCAAGGGAAGAATCATGCTGGAGTCTTGATGATTTTGACGTTGGACGGCCTCTCGGAAAAGGAAAGTTTGGAAACGTTTTCATCTCTCGTGAAAAAAAGACCAAGCGAATCATAGCTTTGAAAGTACTCTTCAAAACACAGTTGCTTCAACTTGGAGTCAGTCATCAGTTGAAGAGAGAGATCGAAATTCAATATCATTTGCGTCATCCGAATATTCTCACTCTTTATGGATACTTTCACGATGACAAGCGTGTGTTCGTCATTCTCGACTATGCCAGCAGAGGAGAATTATTTAATGTCCTCCAATCACAACCTGGACACAAAGTGAATGAGGTCATTGCCGGAAGATTTGTGCGACAGCTGGCCAATGCGTTGCATTACTGCCATTCGAAAGGAGTTATTCACAGAGACATTAAGCCTGAAAATCTTCTTCTTGATTCGAAGCTCAATCTGAAGCTTGCCGATTTCGGATGGTCCGTCGTTGCTGATCACTCGAAACGCCATACATTGTGCGGTACCATGGATTATCTTGCTCCGGAAATGGTTTCCAATCAGCCACATGACTTTAATGTTGACATTTGGGCAATTGGAATTCTTCTCTTCGAAATGCTTGTTGGATATGCTCCGTTCGCCAATCAAACTGGTGATAAATTGATCGCCAGAATCAAGGAGTGCAAGATTTATATTCCAAGTGTTGTGACTGACGGAGCTGCCAGTTTGATAAATGCAATAATCAAAAAGGAACCCCAAGAACGTCTCCCACTTGTTGACATCATGGCTCATCCGTGGATTAAGGAAATGAAGCAACGCGAAGACATTGAAGTTCCACTCTTCATTTCGACGCTCACGAAATCCAGTCGCAATAATTCTACAGCCAATCAATAA | ||
Experiment (4) | ||||
Inhibits (3) | ||||
Species | Caenorhabditis elegans | |||
Reference | WBPaper00003325 | |||
Phenotype | WBPhenotype:0001403 | Remark | In air-1(RNAi) embryos, P-granules and PIE-1 were localized to a single blastomere in approximately half of the examined embryos. In some cases, the staining blastomere was completely anucleate. Although PIE-1 was readily apparent on mitotic centrosomes in wild-type embryos, it was never detected on centrosomes in air-1(RNAi) embryos (n > 200embryos). Defects in P-granule and PIE-1 localization that were observed in 1-cell and 2-cell air-1(RNAi) embryos included the bipolar localization of both P-granules and PIE-1, or bipolar P-granules with PIE-1 localized to only one pole. In older embryos, P-granules were often mislocalized to more than one blastomere and, in the majority of these cases, the PIE-1 protein was undetectable. P-granules were often clumped around many nuclei in older embryos while PIE-1 staining was absent. | |
Remark | (Figure 7, Table 3) air-1 RNAi | |||
Method | RNAi |