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WormBase Tree Display for RNAi: WBRNAi00086071

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Name Class

WBRNAi00086071HomolHomol_homolF56A3:RNAi
Sequence_infoPCR_productsjj_F56A3.4
ExperimentLaboratoryWH
Date09 Nov 2009 00:00:00
GenotypeGFP::GBDwsp-1
Delivered_byBacterial_feeding
InhibitsPredicted_geneF56A3.4Inferred_automaticallyRNAi_primary
GeneWBGene00004955Inferred_automaticallyRNAi_primary
TranscriptF56A3.4.1Inferred_automaticallyRNAi_primary
F56A3.4.2Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00035488
PhenotypeWBPhenotype:0000436RemarkThese embryos did not establish a smoothed cortical domain of GFP::GBDwsp-1, and the CDC-42 activity was located about the site of the previous polar body extrusion. As these embryos developed, the CDC-42 activity of phase II relocalized to the cortical subdomains that were not labeled in phase I. Authors suggest that CDC-42 cortical activity patterns depend upon centrosome function for determination of anterior and posterior cortical domains in the same way that the polarity proteins PAR-6 and PAR-2 do.
RemarkAuthors note that CDC-42 activity is reported by GFP::GBDwsp-1 localization.
MethodRNAi