WormBase Tree Display for RNAi: WBRNAi00082074
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| WBRNAi00082074 | Homol | Homol_homol | F08F8:RNAi | |||
|---|---|---|---|---|---|---|
| Sequence_info | PCR_product | sjj_F08F8.2 | ||||
| Experiment | Laboratory | QC | ||||
| Date | 04 Sep 2009 00:00:00 | |||||
| Strain | WBStrain00034065 | |||||
| Treatment | L3/L4 worms placed on RNAi food and grown to young adults; young adults transferred to fresh RNAi plates with 100 micromolar mevalonate and allowed to lay eggs for 24 hours; adults were removed and progeny were scored at the L4 stage | |||||
| Temperature | 20 | |||||
| Delivered_by | Bacterial_feeding | |||||
| Inhibits | Predicted_gene | F08F8.2 | Inferred_automatically | RNAi_primary | ||
| Gene | WBGene00017268 | Inferred_automatically | RNAi_primary | |||
| Transcript | F08F8.2.1 | Inferred_automatically | RNAi_primary | |||
| Species | Caenorhabditis elegans | |||||
| Reference | WBPaper00035302 | |||||
| Phenotype | WBPhenotype:0001278 | Remark | The presence of mevalonate was able to suppress the the unfolded protein response, as indicated by reduced expression of the hsp-4::gfp transgene, normally induced by RNAi of HMG-CoA reductase (F08F8.2) | |||
| Affected_by | Molecule | WBMol:00004697 | ||||
| EQ_annotations | Life_stage | WBls:0000038 | PATO:0000460 | |||
| Method | RNAi |
