WormBase Tree Display for Interaction: WBInteraction000576896
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| WBInteraction000576896 | Interaction_type | Physical | ProteinProtein | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00004042 | Interactor_type | Bait | |
| WBGene00000875 | Interactor_type | Target | |||
| Interaction_summary | "The key function of PLK1 kinase in RhoA activation during cytokinesis is phosphorylation of the CYK4 N terminus. Phospho-CYK4 binds to a conserved basic surface in the guanine nucleotide exchange factor ECT2. This site is essential for cytokinesis and is distinct from the canonical BRCT phospho-peptide binding site." | ||||
| Detection_method | Reconstituted_complex | ||||
| Throughput | Low_throughput | ||||
| Paper | WBPaper00061884 | ||||
| Remark | fig. S4, in vitro phosphorylation |
