WormBase Tree Display for Interaction: WBInteraction000557486
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| WBInteraction000557486 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003917 | Interactor_type | Trans_regulated | |
| Antibody | WBAntibody00001846 | ||||
| WBGene00003134 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00094718 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "In a wild-type one-cell embryo, the mitotic spindle moves posteriorly during anaphase, giving rise to a larger anterior daughter cell and a smaller posterior cell (Figure 1A)... In Pod embryos, PAR-3 is distributed uniformly throughout the cortex (Figures 1G, 1K, 1O, 1S, and 1W), whereas PAR-2 is missing from the cortex and is instead present in the cytoplasmic foci clustered near microtubule organizing centers (Figures 1H, 1L, 1P, 1T, 1X, and 2G). In embryos from the less penetrant Pod mutant alleles emb-30(g53) and pod-4(or344), PAR-2 can retain reduced cortical localization that is often lateral (Figure 1X)." | ||||
| Detection_method | Antibody | ||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000006 | ||
| Subcellular_localization | posterior cortex | ||||
| Paper | WBPaper00005095 | ||||
| Remark | Fig. 1 |
