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WormBase Tree Display for Interaction: WBInteraction000556222

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Name Class

WBInteraction000556222Interaction_typePhysicalProteinProtein
InteractorInteractor_overlapping_geneWBGene00001194Interactor_typeBait
WBGene00003218Interactor_typeTarget
Interaction_summary"EGL-27(1-1129) was used to screen 3.4 x 10^6 cDNAs, and eight positive cDNAs were identified; three of these cDNAs corresponded to MEP-1. A fragment of MEP-1-containing residues 364-870, which includes all seven zinc-finger domains, was sufficient to interact with full-length EGL-27 in yeast. In addition, MEP-1 residues 330-870 were sufficient to interact with the amino-terminal 637 residues of EGL-27 in yeast (data not shown)."; "The interaction of MEP-1 with full-length EGL-27 was demonstrated to be a direct interaction by a GST-pull-down assay (Figure 5D)"
Detection_methodAffinity_capture_Western
ThroughputLow_throughput
WBProcessWBbiopr:00000020
PaperWBPaper00046298