WormBase Tree Display for Interaction: WBInteraction000543332
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| WBInteraction000543332 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001609 | Interactor_type | Trans_regulator | |
| WBGene00003515 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00000230 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "worms with mutations causing proliferative tumors (mog-6(q465); gld-3(q730) (Belfiore et al., 2004) and glp- 1(ar202) gain of function (Pepper et al., 2003) mutations, respectively) were grown to old age and ectopic expression of MYO-3 was assessed by immunostaining (Figure S5B). Although the tumorous germlines of both mutants were filled with proliferative germ cells, there was no P granule loss or ectopic MYO-3 expression, confirming that muscular differentiation was not simply an age-related process but was specific to the spr-5; let-418 tumorous germlines (Figures S5A and S5B)." | ||||
| Regulation_result | Does_not_regulate | Life_stage | WBls:0000041 | ||
| Anatomy_term | WBbt:0005175 | ||||
| Subcellular_localization | cytoplasm | ||||
| Paper | WBPaper00045158 | ||||
| Remark | Fig. S5; spr-5(by134) mutant background |
