WormBase Tree Display for Interaction: WBInteraction000542443
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| WBInteraction000542443 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00000024 | Interactor_type | Trans_regulated | |
| Molecule_interactor | WBMol:00004852 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "To confirm reduced abu-1 gene expression, transgenic integrated Pabu-1::GFP strain JS4063 was used. Transgenic animals express GFP strongly in the pharynx. Fluorescence intensity in young adults was measured 24 h after exposure to MeHg (125 μM) for 1 h. A higher dose was used for GFP studies since lower doses did not produce observable effects (data not shown). Reduced fluorescence intensity in C. elegans pharynx, especially in the procorpus region was observed in ~30% of the animals (Fig. 3). Three independent experiments were performed for this study." | ||||
| Detection_method | Reporter_gene | [abu-1p::gfp] | |||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Negative_regulate | Life_stage | WBls:0000041 | ||
| Paper | WBPaper00043945 | ||||
| Remark | Fig. 3; MeHg (125uM) |
