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WormBase Tree Display for Interaction: WBInteraction000542372

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Name Class

WBInteraction000542372Interaction_typeRegulatoryChange_of_expression_level
InteractorInteractor_overlapping_geneWBGene00004932Interactor_typeTrans_regulated
TransgeneWBTransgene00000619
ConstructWBCnstr00000617
WBGene00002010Interactor_typeTrans_regulated
TransgeneWBTransgene00005183
ConstructWBCnstr00005160
Molecule_interactorWBMol:00005437Interactor_typeTrans_regulator
Interaction_summary"When we analyzed the activation of UPRmt and ROS defense at day 3 of adulthood, we not only observed a continued activation of UPRmt, but now, unlike the situation at day 1, also a strong activation of the sod-3 promoter in worms treated with AZD2281, NR (Figure 4C), or pme-1 RNAi (Figure S4B)."
Detection_methodConstruct
Reporter_gene[sod-3p::gfp], [hsp-6::gfp]
Transgene
Regulation_levelTranscriptional
Regulation_resultPositive_regulateLife_stageWBls:0000066
PaperWBPaper00043942
RemarkFig. 4C; AZD2281 (100nM)