WormBase Tree Display for Interaction: WBInteraction000534824
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| WBInteraction000534824 | Interaction_type | Physical | ProteinDNA | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00004949 | Interactor_type | Target | |
| WBGene00002987 | Interactor_type | Target | |||
| Feature_interactor | WBsf979156 | Interactor_type | Bait | ||
| Interaction_summary | Our results show specific binding of SOX-2 to both the CEH-36/SOX-2 and LIM-4/ SOX-2 probes, as wild-type unlabeled probes were more efficient at competing with labeled probes in forming the protein-DNA complex than unlabeled probes with mutated SOX-2 binding sites (Appendix Fig S1A and B). CEH-36 and LIM-4 also showed specific binding to the CEH-36/SOX-2 and LIM-4/SOX-2 probes, respectively, since wild-type unlabeled probes were better competitors than the unlabeled probes with a mutated CEH-36 or LIM-4 site. | ||||
| Detection_method | Electrophoretic_mobility_shift_assay | ||||
| Throughput | Low_throughput | ||||
| Paper | WBPaper00048517 |
