WormBase Tree Display for Interaction: WBInteraction000525342
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| WBInteraction000525342 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Change_of_expression_level | |||||
| Interactor | Interactor_overlapping_gene | WBGene00003246 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr11888 | ||||
| Construct | WBCnstr00009186 | ||||
| WBGene00004789 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00091825 | Interactor_type | Trans_regulator | ||
| WBVar00088971 | Interactor_type | Trans_regulator | |||
| Interaction_summary | In wild-type animals, MIG-14::GFP is located on the basolateral membrane and also on dispersed punctate structures in the cytoplasm. In two putative null mutants of sgk-1, ok538 and mg455, the basolateral membrane localization of MIG-14::GFP was hardly detectable, and most of MIG-14::GFP punctate structures localized near the apical membrane and the averaged fluorescence intensity of the cytoplasmic MIG-14::GFP decreased slightly. Thus the subcellular localization of MIG-14 is dependent on SGK-1. | ||||
| Detection_method | Construct | ||||
| Regulation_result | Positive_regulate | Subcellular_localization | basolateral membrane | ||
| Paper | WBPaper00047001 |
