WormBase Tree Display for Interaction: WBInteraction000524088
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| WBInteraction000524088 | Interaction_type | Regulatory | |||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00002992 | Interactor_type | Cis_regulated | |
| Feature_interactor | WBsf919648 | Interactor_type | Cis_regulator | ||
| Interaction_summary | Mutation of the E- box ('CACCTG' to 'CACCAA') on either side of the ACEL impaired the ability of the ACEL to express gfp in the AC. Thus, both of the E-boxes on either side of the FTZ-F1 binding site were necessary to express lin- 3::gfp in the AC. | ||||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000027 | ||
| Anatomy_term | WBbt:0004522 | ||||
| Unaffiliated_expr_pattern | Expr2894 | ||||
| Paper | WBPaper00006370 | ||||
| Remark | As hlh-2 RNAi was initiated at the stages in which lin-3::gfp was already expressed in the AC, the incomplete vulval induction most probably reflects a functional reduction of lin-3 expression in the AC (roughly similar to ablation of the AC during vulval induction). |
