WormBase Tree Display for Interaction: WBInteraction000518924
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| WBInteraction000518924 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003777 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr4897 | ||||
| Transgene | WBTransgene00005229 | ||||
| Construct | WBCnstr00005206 | ||||
| WBGene00017774 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00088046 | Interactor_type | Trans_regulator | ||
| Interaction_summary | Large NMY-2::GFP patches were absent from nop-1(it142) embryos during pseudocleavage. As the pronucleus migrates, small NMY-2::GFP foci are evenly distributed throughout the entire cortex, and cortical flow is greatly attenuated. The anterior cap of smaller myosin puncta forms during prometaphase, though its boundary extends more posteriorly than in control embryos. This cap then dissipates as in control embryos, and discrete, small NMY-2::GFP foci re- accumulate specifically in the equatorial region and induce furrow ingression. Thus, the large myosin foci that appear during pseudocleavage and anaphase in control embryos are NOP-1 dependent. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [nmy-2::gfp] | ||||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000014 | ||
| WBls:0000003 | |||||
| Paper | WBPaper00041462 |
