WormBase Tree Display for Interaction: WBInteraction000518804
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| WBInteraction000518804 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001185 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr1434 | ||||
| Transgene | WBTransgene00000097 | ||||
| Construct | WBCnstr00000097 | ||||
| WBGene00003911 | Interactor_type | Trans_regulator | |||
| WBGene00196764 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00091739 | Interactor_type | Trans_regulator | ||
| WBVar00249451 | Interactor_type | Trans_regulator | |||
| Interaction_summary | Quantitatively, 38% of lin-17 mutants had the normal pattern of egl-17::gfp expression (disregarding morphology); the others had the reversed or the symmetric pattern. In contrast, 64% of lin-17; pak-1(ok448) (P = 0.0104), and 55% of lin-17; pak-1(tm403) (P = 0.0915) mutants had the normal expression pattern, indicating that cam-1 mutations partially suppressed the abnormal pattern of egl-17::gfp expression in lin-17 mutants. Additionally, the percentage of animals with the reversed pattern of egl-17::gfp expression (P7.pa-/P7.pp+) was reduced in lin-17; cam-1 (0%, as compared with 13% in lin-17). | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [egl-17::gfp] | ||||
| Transgene | |||||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Negative_regulate | Anatomy_term | WBbt:0008129 | ||
| Paper | WBPaper00041589 |
