Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Interaction: WBInteraction000503927

expand all nodes | collapse all nodes | view schema

Name Class

WBInteraction000503927Interaction_typeRegulatoryChange_of_expression_level
InteractorInteractor_overlapping_geneWBGene00003598Interactor_typeTrans_regulator
WBGene00000584Interactor_typeTrans_regulated
Variation_interactorWBVar00092097Interactor_typeTrans_regulator
Interaction_summaryEctopic expression of the lsy-6 miRNA from the cog-1 promoter results in the inappropriate downregulation of COG-1::GFP in vulval and uterine tissues. Removing nhl-2 in the context of ectopic lsy-6 expression restores COG-1::GFP expression in uterus.
Detection_methodReporter_gene[cog-1::gfp]
Regulation_levelPost_transcriptional
PaperWBPaper00032974
Remarknhl-2 is required for the efficient posttranscriptional regulation of cog-1 by the lsy-6 miRNA.