WormBase Tree Display for Interaction: WBInteraction000502089
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| WBInteraction000502089 | Interaction_type | Regulatory | |||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00002999 | Interactor_type | Trans_regulator | |
| WBGene00001612 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00090154 | Interactor_type | Trans_regulator | ||
| Interaction_summary | In wild-type nematodes, GLR-1 was detected at synaptic junctions labeled with localized with SNB-1::GFP. In nematodes homozygous for a lin-10 molecular null mutation, GLR-1::RFP failed to be localized at synaptic clusters and accumulated in large structures throughout the dendrite. Presynaptic clusters of SNB-1::GFP were present in lin-10 mutant dendrites, demonstrating that lin-10 is not required for synapse formation or neuronal protein trafficking per se. | ||||
| Detection_method | Reporter_gene | [glr-1::rfp], translational fusion. | |||
| Regulation_result | Positive_regulate | Subcellular_localization | synaptic clusters at synaptic junctions | ||
| Paper | WBPaper00025118 |
