WormBase Tree Display for Interaction: WBInteraction000501874
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| WBInteraction000501874 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003017 | Interactor_type | Trans_regulator | |
| WBGene00001185 | Interactor_type | Trans_regulated | |||
| Expr_pattern | Expr2354 | ||||
| Variation_interactor | WBVar00089401 | Interactor_type | Trans_regulator | ||
| Interaction_summary | During early vulval development (late L2 to L3), egl-17::GFP expression is observed in P6.p and its descendants, fading in early L4. In the mid-L4 stage, GFP expression is seen in the vulC and vulD cells descended from P5.p and P7.p, where it remains throughout adulthood. In lin-31 mutants, GFP expression driven by the full-length promoter or the distal enhancer, but not the proximal enhancer, persisted in vulE and vulF cells from mid-L4 stage through adulthood. | ||||
| Detection_method | Reporter_gene | [egl-17::GFP], transcriptional fusion of full-length or the distal enhancer of egl-17 promoter with GFP | |||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Negative_regulate | Life_stage | WBls:0000038 | ||
| Anatomy_term | WBbt:0006767 | ||||
| WBbt:0006768 | |||||
| Paper | WBPaper00005841 | ||||
| Remark | egl-17 transcription may be regulated by the Ras pathway at least partly through repression, directly or indirectly, by lin-1 and/or lin-31. |
