WormBase Tree Display for Gene: WBGene00303021

WBGene00303021 SMap: S_parent: Sequence: F02A9
  Identity: Version: 3
    Name: CGC_name: mccc-2 Laboratory_evidence: GNW
      Sequence_name: F02A9.10
      Molecular_name: F02A9.10
        F02A9.10.1
        CE00136
      Other_name: CELE_F02A9.10 Accession_evidence: NDB BX284603
      Public_name: mccc-2
    DB_info: Database: NDB locus_tag CELE_F02A9.10
        Panther gene CAEEL|WormBase=WBGene00303021|UniProtKB=P34385
          family PTHR22855
        NCBI gene 41656988
        RefSeq protein NM_001382956.1
        KEGG KEGG_id 6.4.1.4
        NemaPath KEGG_id 6.4.1.4
        SwissProt UniProtAcc P34385
        UniProt_GCRP UniProtAcc P34385
        OMIM gene 609014
    Species: Caenorhabditis elegans
    History: Version_change: 1 06 Mar 2018 14:39:45 WBPerson4025 Event: Split_from: WBGene00008514
        2 09 Mar 2021 13:49:30 WBPerson1983 Name_change: CGC_name: lgc-56
                Other_name: ggr-3
        3 23 Jun 2021 11:39:47 WBPerson1983 Name_change: CGC_name: mccc-2
                Other_name
      Split_from: WBGene00008514
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mccc
    Allele (35)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Contained_in_operon: CEOP5623
    Ortholog (37)
    Paralog: WBGene00018701 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable ATP binding activity and ligase activity. Predicted to contribute to methylcrotonoyl-CoA carboxylase activity. Predicted to be involved in leucine catabolic process. Located in cytoplasm. Human ortholog(s) of this gene implicated in 3-Methylcrotonyl-CoA carboxylase 2 deficiency and mitochondrial metabolism disease. Is an ortholog of human MCCC2 (methylcrotonyl-CoA carboxylase subunit 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080580 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6937)
      DOID:700 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6937)
  Molecular_info: Corresponding_CDS: F02A9.10
    Corresponding_transcript: F02A9.10.1
    Other_sequence (62)
  Experimental_info: RNAi_result: WBRNAi00006030 Inferred_automatically: RNAi_primary
      WBRNAi00109132 Inferred_automatically: RNAi_primary
      WBRNAi00030564 Inferred_automatically: RNAi_primary
      WBRNAi00109935 Inferred_automatically: RNAi_primary
      WBRNAi00109902 Inferred_automatically: RNAi_primary
      WBRNAi00043789 Inferred_automatically: RNAi_primary
      WBRNAi00109989 Inferred_automatically: RNAi_primary
      WBRNAi00012763 Inferred_automatically: RNAi_primary
      WBRNAi00109968 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2012035
      Expr2030271
    Microarray_results (16)
    Expression_cluster (31)
    Interaction: WBInteraction000563821
      WBInteraction000583578
  Map_info: Map: III Position: 0.15767
    Positive: Positive_clone: F02A9 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    Removed the incorrect gene associations of lgc-56 and ggr-3
  Method: Gene