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WormBase Tree Display for Gene: WBGene00229798

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Name Class

WBGene00229798SMapS_parentSequenceBm_v4_ChrX_scaffold_001
IdentityVersion8
NameCGC_nameBma-npp-14From_analysisInferred_from_orthology
Sequence_nameBm9537
Molecular_nameBm9537
Bm9537.1
BM44806
Bm9537.2
Other_nameTAG9537Curator_confirmedWBPerson4055
TAG1254
TAG1933
Bm1_32660Person_evidenceWBPerson5841
Bm1_32670Person_evidenceWBPerson5841
Public_nameBma-npp-14
SpeciesBrugia malayi
HistoryVersion_change110 Dec 2012 14:43:26WBPerson4055EventCreated
203 Sep 2014 17:22:26WBPerson4055EventAcquires_mergeWBGene00221515
303 Sep 2014 17:22:26WBPerson4055EventAcquires_mergeWBGene00222194
420 Mar 2018 10:26:11WBPerson4025Name_changeCGC_nameBma-npp-14
508 Feb 2019 15:42:29WBPerson1983Name_changeCGC_nameRemoved
608 May 2019 10:09:24WBPerson1983Name_changeCGC_nameBma-npp-14
728 May 2021 19:05:21WBPerson1983Name_changeCGC_nameRemoved
828 Jul 2021 11:12:28WBPerson1983Name_changeCGC_nameBma-npp-14
Acquires_mergeWBGene00221515
WBGene00222194
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnpp
RNASeq_FPKM (11)
Ortholog (20)
Structured_descriptionAutomated_descriptionIs affected by 20-hydroxyecdysone and ivermectin based on proteomic and RNA-seq studies. Is predicted to encode a protein with the following domains: Nuclear pore complex protein; Anaphase-promoting complex subunit 4, WD40 domain; Anaphase-promoting complex subunit 4 WD40 domain; WD40/YVTN repeat-like-containing domain superfamily; and WD40 repeat. Is an ortholog of C. elegans npp-14. In C. elegans, npp-14 is involved in negative regulation of execution phase of apoptosis.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSBm9537
Corresponding_transcriptBm9537.1
Bm9537.2
Other_sequence (19)
Experimental_infoExpression_clusterWBPaper00049261:20-hydroxyecdysone_upregulated_protein
WBPaper00049974:ivermectin_1uM_5-day_downregulated
WBPaper00049974:ivermectin_300nM_48h_downregulated
WBPaper00051007:downregulated_M30_vs_L4
WBPaper00051007:downregulated_M120_vs_F120
WBPaper00051007:upregulated_M120_vs_M30
WBPaper00051007:upregulated_M120_vs_M42
ReferenceWBPaper00049974
Remark[190208 pad] The CGC name Bma-npp-14 was deleted as there was no evidence to support it.Curator_confirmedWBPerson1983
[210528 pad] The CGC name Bma-npp-14 was deleted as there was no evidence to support it.Curator_confirmedWBPerson1983
MethodGene