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WormBase Tree Display for Gene: WBGene00022717

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Name Class

WBGene00022717SMapS_parentSequenceZK370
IdentityVersion3
NameCGC_namehipr-1Person_evidenceWBPerson441
Sequence_nameZK370.3
Molecular_nameZK370.3a
ZK370.3a.1
CE00540
ZK370.3b
CE29640
ZK370.3b.1
ZK370.3b.2
Other_namehip-1Paper_evidenceWBPaper00005786
CELE_ZK370.3Accession_evidenceNDBBX284603
Public_namehipr-1
DB_infoDatabaseAceViewgene3J813
WormQTLgeneWBGene00022717
WormFluxgeneWBGene00022717
NDBlocus_tagCELE_ZK370.3
PanthergeneCAEEL|WormBase=WBGene00022717|UniProtKB=Q02328
familyPTHR10407
NCBIgene176224
RefSeqproteinNM_001392161.1
NM_171215.8
SwissProtUniProtAccQ02328
TREEFAMTREEFAM_IDTF316860
UniProt_GCRPUniProtAccQ02328
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:06WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
215 Nov 2007 11:33:13WBPerson2970Name_changeCGC_namehipr-1
308 Aug 2014 15:58:29WBPerson2970Name_changeOther_namehip-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhipr
Allele (74)
StrainWBStrain00002894
WBStrain00031806
WBStrain00055668
RNASeq_FPKM (74)
GO_annotation (24)
Contained_in_operonCEOP3538
Ortholog (44)
ParalogWBGene00006484Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00014864Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionhipr-1 encodes the C. elegans ortholog of mammalian Huntingtin-interacting protein 1-related (Hip1r) and Saccharomyces cerevisiae Sla2p; by homology, HIPR-1 is predicted to function as an actin-clathrin coupling protein; in C. elegans, hipr-1 has been shown to play a role in regulation of cholinergic neurotransmission at the neuromuscular junction and SNB-1 (synaptobrevin) abundance along the ventral nerve cord; an hipr-1 reporter fusion (published as an hip-1 reporter fusion) is expressed in the germline, gonad, pharynx, and several neurons that extend axons along the dorsal and ventral nerve cords.Paper_evidenceWBPaper00004883
WBPaper00031088
WBPaper00005786
Curator_confirmedWBPerson1843
Date_last_updated04 Aug 2014 00:00:00
Automated_descriptionPredicted to enable actin filament binding activity; anion binding activity; and clathrin binding activity. Involved in several processes, including cellular localization; defecation; and ultradian rhythm. Predicted to be located in clathrin-coated vesicle. Expressed in germ line; gonad; neurons; and pharynx. Is an ortholog of human HIP1 (huntingtin interacting protein 1) and HIP1R (huntingtin interacting protein 1 related).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK370.3a
ZK370.3b
Corresponding_transcriptZK370.3a.1
ZK370.3b.1
ZK370.3b.2
Other_sequence (57)
Associated_featureWBsf717091
WBsf717953
WBsf225464
WBsf225465
Experimental_infoRNAi_result (12)
Expr_patternChronogram947
Expr2372
Expr1011416
Expr1040042
Expr1162805
Expr2012437
Expr2030673
Drives_constructWBCnstr00003411
WBCnstr00010795
WBCnstr00024030
Construct_productWBCnstr00010795
WBCnstr00024030
Microarray_results (28)
Expression_cluster (117)
Interaction (126)
Map_infoMapIIIPosition-0.085974Error0.002243
PositivePositive_cloneZK370Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (13)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
This publication refers to ZK370.3 as hip-1. hip-1 is T12D8.8. ZK370.3 is hipr-1Paper_evidenceWBPaper00005786
MethodGene