WormBase Tree Display for Gene: WBGene00022286
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| WBGene00022286 | SMap | S_parent | Sequence | Y75B7AL | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | rga-4 | Person_evidence | WBPerson610 | |||||
| WBPerson351 | |||||||||
| Sequence_name | Y75B7AL.4 | ||||||||
| Molecular_name (21) | |||||||||
| Other_name | CELE_Y75B7AL.4 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | rga-4 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00022286 | |||||
| WormFlux | gene | WBGene00022286 | |||||||
| NDB | locus_tag | CELE_Y75B7AL.4 | |||||||
| Panther | gene | CAEEL|WormBase=Y75B7AL.4c|UniProtKB=A0A0K3AW57 | |||||||
| family | PTHR15670 | ||||||||
| NCBI | gene | 178629 | |||||||
| RefSeq | protein | NM_001313361.3 | |||||||
| NM_001047736.4 | |||||||||
| NM_001313362.3 | |||||||||
| NM_001313363.3 | |||||||||
| NM_001313360.3 | |||||||||
| NM_001313359.5 | |||||||||
| NM_001047737.3 | |||||||||
| TREEFAM | TREEFAM_ID | TF317157 | |||||||
| TrEMBL | UniProtAcc | A0A0K3AT49 | |||||||
| A0A0K3AYE4 | |||||||||
| A0A0K3AW57 | |||||||||
| Q965S4 | |||||||||
| A0A0K3AVE9 | |||||||||
| A0A0K3ASJ8 | |||||||||
| H2KZS7 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A0K3AW57 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 08 Sep 2006 10:43:24 | WBPerson1847 | Name_change | CGC_name | rga-4 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rga | ||||||||
| Allele (251) | |||||||||
| Strain | WBStrain00032278 | ||||||||
| WBStrain00051205 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00001049 | ||||||||
| 00022509 | |||||||||
| 00022510 | |||||||||
| 00022511 | |||||||||
| 00022512 | |||||||||
| 00022513 | |||||||||
| 00022514 | |||||||||
| 00022515 | |||||||||
| 00022516 | |||||||||
| 00126441 | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00019600 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | rga-4 encodes a GTPase-activating protein (GAP); RNAi experiments predicted to target rga-4 and the related rga-3 gene result in early embryonic defects, specifically defects in cortical contractility, non-muscle myosin NMY-2 distribution, and the relative size of PAR protein domains; in vitro, RGA-4 positively regulates RHO-1 GTPase activity, consistent with genetic studies showing that the rga-3/4(RNAi) phenotype requires RHO-1 activity. | Paper_evidence | WBPaper00031005 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Sep 2007 00:00:00 | ||||||||
| Automated_description | Enables GTPase activator activity. Involved in asymmetric protein localization involved in cell fate determination; cortical actin cytoskeleton organization; and regulation of actin filament-based process. Expressed in embryonic cell and germ line. Is an ortholog of human ARHGAP11A (Rho GTPase activating protein 11A). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y75B7AL.4a | |||||||
| Y75B7AL.4b | |||||||||
| Y75B7AL.4c | |||||||||
| Y75B7AL.4d | |||||||||
| Y75B7AL.4e | |||||||||
| Y75B7AL.4f | |||||||||
| Y75B7AL.4g | |||||||||
| Corresponding_CDS_history | Y75B7AL.4:wp88 | ||||||||
| Y75B7AL.4:wp138 | |||||||||
| Y75B7AL.4:wp154 | |||||||||
| Corresponding_transcript | Y75B7AL.4a.1 | ||||||||
| Y75B7AL.4b.1 | |||||||||
| Y75B7AL.4c.1 | |||||||||
| Y75B7AL.4d.1 | |||||||||
| Y75B7AL.4e.1 | |||||||||
| Y75B7AL.4f.1 | |||||||||
| Y75B7AL.4g.1 | |||||||||
| Other_sequence | PT04585 | ||||||||
| CRC04085_1 | |||||||||
| CR07136 | |||||||||
| Tcir_isotig32721 | |||||||||
| EX912288.1 | |||||||||
| HBC08208_1 | |||||||||
| Associated_feature | WBsf668757 | ||||||||
| WBsf668758 | |||||||||
| WBsf668759 | |||||||||
| WBsf999317 | |||||||||
| WBsf999318 | |||||||||
| WBsf1019172 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00058431 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000228 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11005 | ||||||||
| Expr1039835 | |||||||||
| Expr1161851 | |||||||||
| Expr2015316 | |||||||||
| Expr2033550 | |||||||||
| Antibody | WBAntibody00002974 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (108) | |||||||||
| Interaction (12) | |||||||||
| Map_info | Map | V | Position | -19.3971 | Error | 0.068785 | |||
| Positive | Positive_clone | Y75B7AL | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00031005 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00039297 | |||||||||
| WBPaper00041637 | |||||||||
| WBPaper00042325 | |||||||||
| WBPaper00043426 | |||||||||
| WBPaper00044595 | |||||||||
| WBPaper00048425 | |||||||||
| WBPaper00056676 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
