WormBase Tree Display for Gene: WBGene00022279
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| WBGene00022279 | SMap | S_parent | Sequence | Y74C9A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sesn-1 | Person_evidence | WBPerson8420 | |||||
| Sequence_name | Y74C9A.5 | ||||||||
| Molecular_name | Y74C9A.5 | ||||||||
| Y74C9A.5.1 | |||||||||
| CE40291 | |||||||||
| Y74C9A.5.2 | |||||||||
| Other_name | CELE_Y74C9A.5 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | sesn-1 | ||||||||
| DB_info | Database | AceView | gene | 1A502 | |||||
| WormQTL | gene | WBGene00022279 | |||||||
| WormFlux | gene | WBGene00022279 | |||||||
| NDB | locus_tag | CELE_Y74C9A.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00022279|UniProtKB=Q9N4D6 | |||||||
| family | PTHR12474 | ||||||||
| NCBI | gene | 171593 | |||||||
| RefSeq | protein | NM_058263.5 | |||||||
| SwissProt | UniProtAcc | Q9N4D6 | |||||||
| TREEFAM | TREEFAM_ID | TF314230 | |||||||
| UniProt_GCRP | UniProtAcc | Q9N4D6 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 25 Jul 2008 14:36:54 | WBPerson2970 | Name_change | CGC_name | sesn-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sesn | ||||||||
| Allele (105) | |||||||||
| Strain | WBStrain00033001 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (42) | |||||||||
| Structured_description | Concise_description | sesn-1 encodes an ortholog of human sestrins (SESN1, OMIM:606103; SESN2, OMIM:607767; and SESN3, OMIM:607768), a family of p53-regulated proteins required to regenerate peroxiredoxins; like its human orthologs, SESN-1 contains a a predicted redox-active domain homologous to bacterial AhpD. | Paper_evidence | WBPaper00030850 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 13 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable leucine binding activity and oxidoreductase activity, acting on peroxide as acceptor. Predicted to be involved in several processes, including cellular response to leucine; cellular response to leucine starvation; and negative regulation of TORC1 signaling. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SESN1 (sestrin 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y74C9A.5 | |||||||
| Corresponding_CDS_history | Y74C9A.5:wp154 | ||||||||
| Y74C9A.5:wp159 | |||||||||
| Corresponding_transcript | Y74C9A.5.1 | ||||||||
| Y74C9A.5.2 | |||||||||
| Other_sequence | CR07816 | ||||||||
| EL784553.1 | |||||||||
| MIC09415_1 | |||||||||
| CRC09339_1 | |||||||||
| CRC10471_1 | |||||||||
| CR05795 | |||||||||
| FG620133.1 | |||||||||
| Associated_feature | WBsf663852 | ||||||||
| WBsf663853 | |||||||||
| WBsf716901 | |||||||||
| WBsf982373 | |||||||||
| WBsf982374 | |||||||||
| WBsf982375 | |||||||||
| WBsf982376 | |||||||||
| WBsf218863 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00058416 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00117124 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092427 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058415 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1026777 | ||||||||
| Expr1039830 | |||||||||
| Expr1161834 | |||||||||
| Expr2015753 | |||||||||
| Expr2033986 | |||||||||
| Drives_construct | WBCnstr00022572 | ||||||||
| WBCnstr00024298 | |||||||||
| Construct_product | WBCnstr00022572 | ||||||||
| WBCnstr00024298 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (123) | |||||||||
| Interaction | WBInteraction000042588 | ||||||||
| WBInteraction000161049 | |||||||||
| Map_info | Map | I | Position | -21.2707 | Error | 0.194035 | |||
| Positive | Positive_clone | Y74C9A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00037706 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041986 | |||||||||
| WBPaper00043024 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059186 | |||||||||
| WBPaper00061997 | |||||||||
| WBPaper00064339 | |||||||||
| WBPaper00064506 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
