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WormBase Tree Display for Gene: WBGene00021929

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Name Class

WBGene00021929SMapS_parentSequenceY55F3AM
IdentityVersion3
NameCGC_namedcap-1Person_evidenceWBPerson1787
Sequence_nameY55F3AM.12
Molecular_nameY55F3AM.12
Y55F3AM.12.1
CE22543
Other_namedcp1Paper_evidenceWBPaper00026846
CELE_Y55F3AM.12Accession_evidenceNDBBX284604
Public_namedcap-1
DB_infoDatabaseAceViewgene4B806
WormQTLgeneWBGene00021929
WormFluxgeneWBGene00021929
NDBlocus_tagCELE_Y55F3AM.12
PanthergeneCAEEL|WormBase=WBGene00021929|UniProtKB=Q9N363
familyPTHR16290
NCBIgene176924
RefSeqproteinNM_067629.7
SwissProtUniProtAccQ9N363
TREEFAMTREEFAM_IDTF320504
UniProt_GCRPUniProtAccQ9N363
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
201 Apr 2005 11:05:24WBPerson2970Name_changeCGC_namedcap-1
319 Dec 2005 14:45:01WBPerson2970Name_changeOther_namedcp1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdcap
Allele (53)
StrainWBStrain00002810
WBStrain00036759
RNASeq_FPKM (74)
GO_annotation (32)
Ortholog (40)
Structured_descriptionConcise_descriptiondcap-1 encodes an ortholog of budding yeast Dcp1p and human DCP1A(OMIM:607010) and DCP1B (OMIM:609843); DCAP-1 is expressed in diversetissues, including muscle, intestine, neurons, and the reproductivesystem; DCAP-1 is colocalized with CAR-1 to P granules, and with AIN-1and CAR-1 to discrete cytoplasmic foci that resemble P bodies; althoughit is orthologous to mRNA decapping complex subunits, DCAP-1 itselfshows no decapping activity in vitro on either m7GpppG- orm2,2,7GpppG-capped RNAs; however, dcap-1(RNAi) shows weak syntheticlethality with dcap-2(RNAi), suggesting that DCAP-1 and DCAP-2 arepartially redundant in vivo.Paper_evidenceWBPaper00006525
WBPaper00024397
WBPaper00026707
WBPaper00026846
WBPaper00026933
WBPaper00028410
WBPaper00029287
Curator_confirmedWBPerson567
Date_last_updated02 May 2007 00:00:00
Automated_descriptionPredicted to enable mRNA binding activity. Involved in several processes, including determination of adult lifespan; nematode larval development; and response to heat. Located in P granule and P-body. Expressed in head; motor neurons; neurons; tail; and touch receptor neurons. Is an ortholog of human DCP1A (decapping mRNA 1A) and DCP1B (decapping mRNA 1B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY55F3AM.12
Corresponding_transcriptY55F3AM.12.1
Other_sequenceAcan_isotig08404
CRC01295_1
CBC07589_1
CR01929
CR09392
Associated_featureWBsf651635
WBsf229736
WBsf229737
Experimental_infoRNAi_resultWBRNAi00082155Inferred_automaticallyRNAi_primary
WBRNAi00021047Inferred_automaticallyRNAi_primary
WBRNAi00021044Inferred_automaticallyRNAi_primary
WBRNAi00082157Inferred_automaticallyRNAi_primary
WBRNAi00057523Inferred_automaticallyRNAi_primary
Expr_pattern (13)
Drives_constructWBCnstr00003337
WBCnstr00009614
WBCnstr00019819
WBCnstr00019820
WBCnstr00019827
WBCnstr00024401
Construct_productWBCnstr00005580
WBCnstr00018462
WBCnstr00019222
WBCnstr00019820
WBCnstr00019827
WBCnstr00024401
Regulate_expr_clusterWBPaper00065043:dcap-1(tm3163)_downregulated
WBPaper00065043:dcap-1(tm3163)_upregulated
AntibodyWBAntibody00000956
Microarray_results (26)
Expression_cluster (110)
Interaction (39)
Map_infoMapIVPosition-22.4137Error0.043406
PositivePositive_cloneY55F3AMInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (16)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene