WormBase Tree Display for Gene: WBGene00021789
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| WBGene00021789 | SMap | S_parent | Sequence | Y51H7C | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | nol-6 | |||||||
| Sequence_name | Y51H7C.11 | ||||||||
| Molecular_name | Y51H7C.11 | ||||||||
| Y51H7C.11.1 | |||||||||
| CE53914 | |||||||||
| Other_name | rpa-6 | Paper_evidence | WBPaper00035215 | ||||||
| Y51H7C.g | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| rpa-9 | Remark | Name retired 2010-02-05_11:20:57 | |||||||
| CELE_Y51H7C.11 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | nol-6 | ||||||||
| DB_info | Database | AceView | gene | 2B716 | |||||
| WormQTL | gene | WBGene00021789 | |||||||
| WormFlux | gene | WBGene00021789 | |||||||
| NDB | locus_tag | CELE_Y51H7C.11 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00021789|UniProtKB=Q95XY4 | |||||||
| family | PTHR17972 | ||||||||
| NCBI | gene | 173520 | |||||||
| RefSeq | protein | NM_001377698.2 | |||||||
| TrEMBL | UniProtAcc | Q95XY4 | |||||||
| UniProt_GCRP | UniProtAcc | Q95XY4 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 17 Aug 2007 14:29:26 | WBPerson2970 | Name_change | CGC_name | nol-6 | ||||
| 3 | 05 Feb 2010 11:20:57 | WBPerson2970 | Name_change | Other_name | rpa-9 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nol | ||||||||
| Allele (307) | |||||||||
| Strain | WBStrain00003401 | ||||||||
| WBStrain00000321 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (38) | |||||||||
| Structured_description | Concise_description | nol-6 encodes a nucleolar RNA-associated protein (NRAP); in addition to its predicted role in ribosome biogenesis and thus, nucleolar integrity, genetic analysis indicates that nol-6, along with other nucleolar proteins, plays a role in regulation of innate immunity: loss of nol-6 activity via RNAi results in increased resistance to infection by bacterial pathogens in a manner dependent upon cep-1/p53 and sym-1, which encodes a leucine-rich repeat protein, and whose transcription is positively regulated by CEP-1; enhanced resistance of nol-6 mutant animals to P. aeruginosa is also dependent upon DAF-16 and PMK-1. | Paper_evidence | WBPaper00028948 | |||||
| WBPaper00035215 | |||||||||
| WBPaper00035613 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 19 Jan 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA binding activity. Involved in negative regulation of innate immune response. Predicted to be located in condensed nuclear chromosome and nucleolus. Predicted to be part of CURI complex; UTP-C complex; and small-subunit processome. Is an ortholog of human NOL6 (nucleolar protein 6). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y51H7C.11 | |||||||
| Corresponding_CDS_history | Y51H7C.11:wp94 | ||||||||
| Y51H7C.11:wp149 | |||||||||
| Y51H7C.11:wp274 | |||||||||
| Corresponding_transcript | Y51H7C.11.1 | ||||||||
| Other_sequence (19) | |||||||||
| Associated_feature | WBsf986681 | ||||||||
| WBsf986682 | |||||||||
| WBsf986683 | |||||||||
| WBsf1011550 | |||||||||
| WBsf1011551 | |||||||||
| WBsf1011552 | |||||||||
| WBsf222689 | |||||||||
| Experimental_info | RNAi_result (15) | ||||||||
| Expr_pattern | Chronogram356 | ||||||||
| Expr7029 | |||||||||
| Expr1012183 | |||||||||
| Expr1039558 | |||||||||
| Expr1160642 | |||||||||
| Expr2014351 | |||||||||
| Expr2032592 | |||||||||
| Drives_construct | WBCnstr00003869 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (90) | |||||||||
| Interaction (38) | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| Map_info | Map | II | Position | -15.4493 | Error | 0.002749 | |||
| Positive | Positive_clone | Y51H7C | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00035215 | ||||||||
| WBPaper00035613 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00047105 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061436 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
