WormBase Tree Display for Gene: WBGene00021304
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| WBGene00021304 | SMap | S_parent | Sequence | Y32G9A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | nphp-2 | Paper_evidence | WBPaper00040842 | |||||
| Sequence_name | Y32G9A.6 | ||||||||
| Molecular_name (20) | |||||||||
| Other_name | CELE_Y32G9A.6 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | nphp-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:04 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 11 Apr 2012 13:49:30 | WBPerson2970 | Name_change | CGC_name | nphp-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nphp | ||||||||
| Allele (226) | |||||||||
| Strain | WBStrain00036591 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00000990 | ||||||||
| 00000991 | |||||||||
| 00092081 | |||||||||
| 00092082 | |||||||||
| 00092083 | |||||||||
| Ortholog (16) | |||||||||
| Paralog | WBGene00006780 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | nphp-2 encodes an ankyrin repeat domain-containing protein orthologous to mammalian inversin (INVS); NPHP-2 activity is required for ciliogenesis; in regulating ciliogenesis, nphp-2 functions together with nphp-1, nphp-2, and mks-1, mks-3, mks-6, mksr-1 and mksr-2; NPHP-2 localizes to the middle segment of sensory cilium (nonmotile primary cilium). | Paper_evidence | WBPaper00040842 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 23 Oct 2014 00:00:00 | ||||||||
| Automated_description | Involved in protein localization to ciliary inversin compartment. Located in ciliary inversin compartment. Expressed in neurons. Human ortholog(s) of this gene implicated in hypertension and nephronophthisis 2. Is an ortholog of human INVS (inversin). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111113 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17870) | ||||
| DOID:10763 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17870) | ||||||
| Molecular_info | Corresponding_CDS | Y32G9A.6a | |||||||
| Y32G9A.6b | |||||||||
| Y32G9A.6c | |||||||||
| Y32G9A.6d | |||||||||
| Y32G9A.6e | |||||||||
| Y32G9A.6f | |||||||||
| Corresponding_CDS_history | Y32G9A.6:wp231 | ||||||||
| Corresponding_transcript | Y32G9A.6g | ||||||||
| Y32G9A.6h | |||||||||
| Y32G9A.6a.1 | |||||||||
| Y32G9A.6b.1 | |||||||||
| Y32G9A.6c.1 | |||||||||
| Y32G9A.6d.1 | |||||||||
| Y32G9A.6e.1 | |||||||||
| Y32G9A.6f.1 | |||||||||
| Other_sequence | JI468614.1 | ||||||||
| JI479380.1 | |||||||||
| Acan_isotig04188 | |||||||||
| ASC39508_1 | |||||||||
| JI467427.1 | |||||||||
| FE909386.1 | |||||||||
| JI166629.1 | |||||||||
| JI166462.1 | |||||||||
| Associated_feature | WBsf047485 | ||||||||
| WBsf646687 | |||||||||
| WBsf646688 | |||||||||
| WBsf718287 | |||||||||
| WBsf999415 | |||||||||
| WBsf999416 | |||||||||
| WBsf1019235 | |||||||||
| WBsf1019236 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00055798 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr3730 | ||||||||
| Expr9983 | |||||||||
| Expr9984 | |||||||||
| Expr14514 | |||||||||
| Expr1020265 | |||||||||
| Expr1039287 | |||||||||
| Expr1159332 | |||||||||
| Expr2014366 | |||||||||
| Expr2032607 | |||||||||
| Drives_construct | WBCnstr00011634 | ||||||||
| WBCnstr00014987 | |||||||||
| WBCnstr00014988 | |||||||||
| WBCnstr00041066 | |||||||||
| Construct_product | WBCnstr00014988 | ||||||||
| WBCnstr00041066 | |||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (100) | |||||||||
| Map_info | Map | V | Position | -16.8496 | |||||
| Positive | Positive_clone | Y32G9A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00026601 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00040842 | |||||||||
| WBPaper00044991 | |||||||||
| WBPaper00045913 | |||||||||
| WBPaper00046152 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00063946 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
