WormBase Tree Display for Gene: WBGene00021043
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WBGene00021043 | SMap | S_parent | Sequence | W05G11 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | pck | |||||
Allele (218) | ||||||
Strain | WBStrain00032381 | |||||
RNASeq_FPKM (74) | ||||||
GO_annotation (24) | ||||||
Ortholog (41) | ||||||
Paralog | WBGene00011232 | Caenorhabditis elegans | From_analysis | Panther | ||
WormBase-Compara | ||||||
WBGene00019151 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | ||||||
Structured_description | Concise_description | pck-1 is one of three C. elegans genes that encode proteins with similarity to phosphoenolpyruvate carboxykinase (PEPCK); by similarity, the products of W05G11.6 are predicted to function in gluconeogenesis. | Curator_confirmed | WBPerson1843 | ||
Date_last_updated | 27 Jul 2012 00:00:00 | |||||
Automated_description | Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Located in cytosol and striated muscle dense body. Expressed in several structures, including body wall musculature; preanal ganglion; somatic nervous system; tail ganglion; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | |
DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | |||
Molecular_info | Corresponding_CDS | W05G11.6 | ||||
Corresponding_CDS_history | W05G11.6b:wp275 | |||||
W05G11.6d:wp275 | ||||||
Corresponding_transcript | W05G11.6.1 | |||||
Other_sequence (167) | ||||||
Associated_feature (15) | ||||||
Experimental_info | RNAi_result (13) | |||||
Expr_pattern | Expr9397 | |||||
Expr15024 | ||||||
Expr15026 | ||||||
Expr1024494 | ||||||
Expr1039172 | ||||||
Expr1158379 | ||||||
Expr2014778 | ||||||
Expr2033012 | ||||||
Drives_construct | WBCnstr00041522 | |||||
WBCnstr00041875 | ||||||
WBCnstr00041876 | ||||||
Construct_product | WBCnstr00013962 | |||||
WBCnstr00041876 | ||||||
WBCnstr00042950 | ||||||
WBCnstr00042951 | ||||||
Microarray_results (39) | ||||||
Expression_cluster (317) | ||||||
Interaction (47) | ||||||
Map_info | Map | III | Position | -27.1341 | ||
Positive | Positive_clone | W05G11 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference (16) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |