WormBase Tree Display for Gene: WBGene00020447
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| WBGene00020447 | SMap | S_parent | Sequence | T12B3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mob-3 | |||||||
| Sequence_name | T12B3.4 | ||||||||
| Molecular_name | T12B3.4a | ||||||||
| T12B3.4a.1 | |||||||||
| CE21179 | |||||||||
| T12B3.4b | |||||||||
| CE49546 | |||||||||
| T12B3.4b.1 | |||||||||
| T12B3.4b.2 | |||||||||
| T12B3.4b.3 | |||||||||
| Other_name | T12B3.a | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_T12B3.4 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | mob-3 | ||||||||
| DB_info | Database | AceView | gene | 4I150 | |||||
| WormQTL | gene | WBGene00020447 | |||||||
| WormFlux | gene | WBGene00020447 | |||||||
| NDB | locus_tag | CELE_T12B3.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00020447|UniProtKB=Q9UAX1 | |||||||
| family | PTHR22599 | ||||||||
| NCBI | gene | 177511 | |||||||
| RefSeq | protein | NM_001307275.5 | |||||||
| NM_068778.4 | |||||||||
| TrEMBL | UniProtAcc | W6RY92 | |||||||
| Q9UAX1 | |||||||||
| UniProt_GCRP | UniProtAcc | Q9UAX1 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 05 Apr 2017 11:17:23 | WBPerson2970 | Name_change | CGC_name | mob-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mob | ||||||||
| Allele (50) | |||||||||
| Strain | WBStrain00033042 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00100738 | ||||||||
| 00100739 | |||||||||
| 00100740 | |||||||||
| 00100741 | |||||||||
| 00100742 | |||||||||
| 00100743 | |||||||||
| 00100744 | |||||||||
| Ortholog (43) | |||||||||
| Paralog | WBGene00008601 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00009551 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00016238 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | T12B3.4 encodes one of three C. elegans proteins orthologous to members of the MOB (Mps One Binder) family of proteins, a group of highly conserved proteins that function as binding partners and co-activators of NDR/LATS protein kinases; in metazoans, MOB proteins are core components of the Hippo signaling pathway that regulates cell proliferation and survival. | Paper_evidence | WBPaper00005453 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 22 Feb 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein kinase activator activity. Predicted to be involved in positive regulation of protein phosphorylation and signal transduction. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human MOB3A (MOB kinase activator 3A) and MOB3B (MOB kinase activator 3B). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T12B3.4a | |||||||
| T12B3.4b | |||||||||
| Corresponding_transcript | T12B3.4a.1 | ||||||||
| T12B3.4b.1 | |||||||||
| T12B3.4b.2 | |||||||||
| T12B3.4b.3 | |||||||||
| Other_sequence (83) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00078438 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00053177 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1017221 | ||||||||
| Expr1038919 | |||||||||
| Expr1156771 | |||||||||
| Expr2013639 | |||||||||
| Expr2031873 | |||||||||
| Drives_construct | WBCnstr00025133 | ||||||||
| Construct_product | WBCnstr00025133 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (122) | |||||||||
| Interaction (51) | |||||||||
| Map_info | Map | IV | Position | 3.33297 | |||||
| Positive | Positive_clone | T12B3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005453 | ||||||||
| WBPaper00034040 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
