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WormBase Tree Display for Gene: WBGene00020172

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Name Class

WBGene00020172SMapS_parentSequenceT02H6
IdentityVersion2
NameCGC_namethoc-1Person_evidenceWBPerson4055
Sequence_nameT02H6.2
Molecular_nameT02H6.2
T02H6.2.1
CE36887
Other_nameCELE_T02H6.2Accession_evidenceNDBBX284602
Public_namethoc-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:02WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
220 Jul 2007 11:50:19WBPerson2970Name_changeCGC_namethoc-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classthoc
Allele (86)
In_clusterconserved_RDE-1_cluster
conserved_miRNA_siRNA_cluster
RNASeq_FPKM (74)
GO_annotation00095383
00095384
00095385
00095386
Contained_in_operonCEOP2032
Ortholog (32)
Structured_descriptionConcise_descriptionthoc-1 encodes the C. elegans ortholog of mammalian THOC1 and Drosophila and S. cerevisiae Hpr1, conserved subunits of the THO complex involved in mRNP biogenesis as part of transcription elongation, mRNA maturation, and export.Paper_evidenceWBPaper00041879
Curator_confirmedWBPerson1843
Date_last_updated09 Jan 2013 00:00:00
Automated_descriptionPredicted to be involved in mRNA export from nucleus and regulation of DNA-templated transcription elongation. Predicted to be part of THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Is an ortholog of human THOC1 (THO complex subunit 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050564Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19070)
Molecular_infoCorresponding_CDST02H6.2
Corresponding_CDS_historyT02H6.2:wp125
Corresponding_transcriptT02H6.2.1
Other_sequenceAcan_isotig12471
CBC02614_1
Dviv_isotig23563
Acan_isotig15547
Oden_isotig18662
HBC00624_1
Hbac_isotig02112
EX915874.1
CGC01399_1
Associated_featureWBsf986466
WBsf986467
WBsf986468
WBsf1011425
WBsf1011426
Experimental_infoRNAi_resultWBRNAi00052245Inferred_automaticallyRNAi_primary
Expr_patternExpr13876
Expr1025250
Expr1038774
Expr1155876
Expr2017389
Expr2035528
Construct_productWBCnstr00040224
Microarray_results (24)
Expression_cluster (67)
InteractionWBInteraction000113189
WBInteraction000158093
WBInteraction000397442
WBInteraction000450396
WBInteraction000454607
WBInteraction000558574
WBInteraction000558575
WBInteraction000558576
WBInteraction000567842
WBInteraction000570499
Map_infoMapIIPosition-15.5915Error0.00013
PositivePositive_cloneT02H6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00041879
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene