WormBase Tree Display for Gene: WBGene00019832
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WBGene00019832 | SMap | S_parent | Sequence | R02F2 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | osg-1 | Person_evidence | WBPerson3192 | |||
Sequence_name | R02F2.2 | ||||||
Molecular_name | R02F2.2 | ||||||
R02F2.2.1 | |||||||
CE39517 | |||||||
Other_name | CELE_R02F2.2 | Accession_evidence | NDB | BX284603 | |||
Public_name | osg-1 | ||||||
DB_info | Database | AceView | gene | 3G587 | |||
WormQTL | gene | WBGene00019832 | |||||
WormFlux | gene | WBGene00019832 | |||||
NDB | locus_tag | CELE_R02F2.2 | |||||
Panther | gene | CAEEL|WormBase=WBGene00019832|UniProtKB=Q21653 | |||||
family | PTHR12877 | ||||||
NCBI | gene | 175756 | |||||
RefSeq | protein | NM_065771.7 | |||||
SwissProt | UniProtAcc | Q21653 | |||||
TREEFAM | TREEFAM_ID | TF317017 | |||||
UniProt_GCRP | UniProtAcc | Q21653 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | osg | ||||||
Allele (160) | |||||||
Strain | WBStrain00032256 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00072344 | ||||||
00072345 | |||||||
00072346 | |||||||
00124595 | |||||||
Ortholog (54) | |||||||
Structured_description | Concise_description | R02F2.2 encodes a guanine nucleotide exchange factor of the Dbl family; R02F2.2 plays a role in aging, and appears to be recruited, under conditions of oxidative stress, to effect loss of neuronal function via dysregulation of RHO-1 GTPase-mediated signaling and subsequent effects on the actin cytoskeleton and actin dynamics; an R02F2.2::GFP reporter fusion is expressed in body wall muscles, head muscles, and in several neurons in the head, including the ASE and FLP neurons. | Paper_evidence | WBPaper00046168 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 22 Dec 2014 00:00:00 | ||||||
Automated_description | Predicted to enable guanyl-nucleotide exchange factor activity. Involved in response to oxidative stress. Expressed in body wall musculature and head neurons. Is an ortholog of human ARHGEF17 (Rho guanine nucleotide exchange factor 17). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | R02F2.2 | |||||
Corresponding_CDS_history | R02F2.2:wp152 | ||||||
Corresponding_transcript | R02F2.2.1 | ||||||
Other_sequence | JI227717.1 | ||||||
Oden_isotig22983 | |||||||
JI215742.1 | |||||||
Name_isotig07645 | |||||||
NAC01448_1 | |||||||
BU086801.1 | |||||||
Associated_feature | WBsf645172 | ||||||
WBsf992406 | |||||||
WBsf992407 | |||||||
WBsf992408 | |||||||
WBsf1014892 | |||||||
WBsf1014893 | |||||||
WBsf1014894 | |||||||
WBsf224935 | |||||||
Experimental_info | RNAi_result (11) | ||||||
Expr_pattern | Expr8758 | ||||||
Expr12108 | |||||||
Expr1024754 | |||||||
Expr1038597 | |||||||
Expr1154862 | |||||||
Expr2014638 | |||||||
Expr2032871 | |||||||
Drives_construct | WBCnstr00005768 | ||||||
WBCnstr00020214 | |||||||
WBCnstr00025562 | |||||||
Construct_product | WBCnstr00025562 | ||||||
Microarray_results (22) | |||||||
Expression_cluster (172) | |||||||
Interaction | WBInteraction000185628 | ||||||
WBInteraction000321442 | |||||||
WBInteraction000371190 | |||||||
WBInteraction000426809 | |||||||
Map_info | Map | III | Position | -1.61478 | |||
Positive | Positive_clone | R02F2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (5) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |