WormBase Tree Display for Gene: WBGene00017766
expand all nodes | collapse all nodes | view schema
| WBGene00017766 | SMap | S_parent | Sequence | F25B4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | peli-1 | Person_evidence | WBPerson260 | |||||
| Sequence_name | F25B4.2 | ||||||||
| Molecular_name | F25B4.2 | ||||||||
| F25B4.2.1 | |||||||||
| CE30760 | |||||||||
| F25B4.2.2 | |||||||||
| Other_name | CELE_F25B4.2 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | peli-1 | ||||||||
| DB_info | Database | AceView | gene | 5G191 | |||||
| WormQTL | gene | WBGene00017766 | |||||||
| WormFlux | gene | WBGene00017766 | |||||||
| NDB | locus_tag | CELE_F25B4.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00017766|UniProtKB=Q22967 | |||||||
| family | PTHR12098 | ||||||||
| NCBI | gene | 178959 | |||||||
| RefSeq | protein | NM_001383308.2 | |||||||
| TREEFAM | TREEFAM_ID | TF314338 | |||||||
| TrEMBL | UniProtAcc | Q22967 | |||||||
| UniProt_GCRP | UniProtAcc | Q22967 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 09 Dec 2014 15:51:18 | WBPerson2970 | Name_change | CGC_name | peli-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | peli | ||||||||
| Allele (103) | |||||||||
| Strain | WBStrain00002531 | ||||||||
| WBStrain00002532 | |||||||||
| WBStrain00002684 | |||||||||
| WBStrain00002725 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00076856 | ||||||||
| 00076857 | |||||||||
| 00123080 | |||||||||
| 00123081 | |||||||||
| 00123082 | |||||||||
| Ortholog (43) | |||||||||
| Structured_description | Concise_description | F25B4.2 encodes a protein with similarity to the Pellino family of E3 ubiquitin ligases that function in regulation of Toll signaling; loss of F25B4.2 activity via RNAi results in embryonic arrest; an F25B4.2::mCherry promoter fusion is expressed in ciliated neurons, including the ASK, ADL, ASI, ASH, ASJ, PHA and PHB neurons, and in muscle cells during larval development; F25B4.2 expression in ciliated neurons is dependent upon the DAF-19 regulatory factor X (RFX) transcription factor; the product of F25B4.2 has been shown to physically interact with the MEX-3 KH domain protein. | Paper_evidence | WBPaper00005160 | |||||
| WBPaper00024209 | |||||||||
| WBPaper00040183 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 15 Sep 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination. Expressed in chemosensory neurons; ciliated neurons; and head. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human PELI2 (pellino E3 ubiquitin protein ligase family member 2) and PELI3 (pellino E3 ubiquitin protein ligase family member 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8827) | ||||
| Molecular_info | Corresponding_CDS | F25B4.2 | |||||||
| Corresponding_transcript | F25B4.2.1 | ||||||||
| F25B4.2.2 | |||||||||
| Other_sequence (30) | |||||||||
| Associated_feature | WBsf655091 | ||||||||
| WBsf1000069 | |||||||||
| WBsf1000070 | |||||||||
| WBsf231789 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00013846 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00045466 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00083272 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (13) | |||||||||
| Drives_construct (11) | |||||||||
| Construct_product | WBCnstr00027037 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (117) | |||||||||
| Interaction (15) | |||||||||
| Map_info | Map | V | Position | -1.16999 | |||||
| Positive | Positive_clone | F25B4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00039675 | |||||||||
| WBPaper00040183 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00063946 | |||||||||
| WBPaper00065747 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
