WormBase Tree Display for Gene: WBGene00017699
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WBGene00017699 | SMap | S_parent | Sequence | F22D3 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | flcn | |||||
Allele (252) | ||||||
Strain | WBStrain00031743 | |||||
RNASeq_FPKM (74) | ||||||
GO_annotation (20) | ||||||
Ortholog (40) | ||||||
Structured_description | Concise_description | F22D3.2 encodes an ortholog of human folliculin (OMIM:607273, mutated inBirt-Hogg-Dube syndrome). | Paper_evidence | WBPaper00028837 | ||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 11 Dec 2006 00:00:00 | |||||
Automated_description | Predicted to contribute to GTPase activator activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of TORC1 signaling; and positive regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in cytosol. Expressed in excretory cell; nervous system; spermatheca; and vulva. Used to study Birt-Hogg-Dube syndrome. Human ortholog(s) of this gene implicated in several diseases, including Birt-Hogg-Dube syndrome; primary spontaneous pneumothorax; and renal cell carcinoma. Is an ortholog of human FLCN (folliculin). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info (2) | ||||||
Models_disease_in_annotation | WBDOannot00000382 | |||||
Molecular_info | Corresponding_CDS | F22D3.2c | ||||
F22D3.2d | ||||||
F22D3.2e | ||||||
F22D3.2f | ||||||
F22D3.2g | ||||||
F22D3.2i | ||||||
F22D3.2j | ||||||
Corresponding_CDS_history | F22D3.2:wp127 | |||||
F22D3.2a:wp206 | ||||||
F22D3.2a:wp238 | ||||||
F22D3.2a:wp274 | ||||||
F22D3.2b:wp206 | ||||||
F22D3.2b:wp238 | ||||||
F22D3.2h:wp274 | ||||||
Corresponding_transcript | F22D3.2c.1 | |||||
F22D3.2d.1 | ||||||
F22D3.2e.1 | ||||||
F22D3.2f.1 | ||||||
F22D3.2g.1 | ||||||
F22D3.2i.1 | ||||||
F22D3.2j.1 | ||||||
Other_sequence (21) | ||||||
Associated_feature (63) | ||||||
Experimental_info | RNAi_result | WBRNAi00013748 | Inferred_automatically | RNAi_primary | ||
WBRNAi00045306 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00013747 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00031265 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00092437 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00092428 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr10985 | |||||
Expr13864 | ||||||
Expr1017397 | ||||||
Expr1037596 | ||||||
Expr1149230 | ||||||
Expr2011814 | ||||||
Expr2030052 | ||||||
Drives_construct | WBCnstr00017598 | |||||
WBCnstr00017614 | ||||||
WBCnstr00027093 | ||||||
Construct_product | WBCnstr00017614 | |||||
WBCnstr00027093 | ||||||
WBCnstr00040219 | ||||||
Regulate_expr_cluster | WBPaper00042236:flcn-1(ok975)_upregulated | |||||
WBPaper00056471:flcn-1(ok975)_downregulated | ||||||
WBPaper00056471:flcn-1(ok975)_upregulated | ||||||
Antibody | WBAntibody00002522 | |||||
Microarray_results (41) | ||||||
Expression_cluster (164) | ||||||
Interaction | WBInteraction000402369 | |||||
WBInteraction000520210 | ||||||
WBInteraction000520211 | ||||||
WBInteraction000520212 | ||||||
WBInteraction000520213 | ||||||
WBInteraction000520218 | ||||||
WBInteraction000521811 | ||||||
WBInteraction000534849 | ||||||
Map_info | Map | II | Position | 0.145905 | ||
Positive | Positive_clone | F22D3 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference | WBPaper00038491 | |||||
WBPaper00042236 | ||||||
WBPaper00043118 | ||||||
WBPaper00048129 | ||||||
WBPaper00048631 | ||||||
WBPaper00049821 | ||||||
WBPaper00051847 | ||||||
WBPaper00055071 | ||||||
WBPaper00055090 | ||||||
WBPaper00061202 | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |