WormBase Tree Display for Gene: WBGene00017075
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| WBGene00017075 | SMap | S_parent | Sequence | D2096 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | nap-1 | Person_evidence | WBPerson260 | |||||
| Sequence_name | D2096.8 | ||||||||
| Molecular_name | D2096.8 | ||||||||
| D2096.8.1 | |||||||||
| CE04306 | |||||||||
| Other_name | nsbp-1 | Paper_evidence | WBPaper00041864 | ||||||
| CELE_D2096.8 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | nap-1 | ||||||||
| DB_info | Database | AceView | gene | 4J144 | |||||
| WormQTL | gene | WBGene00017075 | |||||||
| WormFlux | gene | WBGene00017075 | |||||||
| NDB | locus_tag | CELE_D2096.8 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00017075|UniProtKB=Q19007 | |||||||
| family | PTHR11875 | ||||||||
| NCBI | gene | 177636 | |||||||
| RefSeq | protein | NM_069021.9 | |||||||
| TREEFAM | TREEFAM_ID | TF314349 | |||||||
| TrEMBL | UniProtAcc | Q19007 | |||||||
| UniProt_GCRP | UniProtAcc | Q19007 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 13 Oct 2011 15:59:42 | WBPerson2970 | Name_change | CGC_name | nap-1 | ||||
| 3 | 09 Jan 2013 14:46:09 | WBPerson2970 | Name_change | Other_name | nsbp-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nap | ||||||||
| Allele (33) | |||||||||
| Strain | WBStrain00049522 | ||||||||
| WBStrain00049552 | |||||||||
| WBStrain00049792 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Contained_in_operon | CEOP4288 | ||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00005007 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | D2096.8 encodes a protein related in sequence to the conserved NAP (Nucleosome Assembly Protein) family of proteins involved in chromatin remodeling; loss of D2096.8 activity in wild-type and various mutant backgrounds suggests that, in C. elegans, the product of D2096.8 is required for proper transcriptional regulation that affects a number of biological processes including embryonic and larval development, body morphology, locomotion, and vulval formation; the protein product of D2096.8 is present at significantly lower levels in daf-2 mutant vs. wild-type adult animals during a temperature shift from 15 to 25 degrees C. | Paper_evidence | WBPaper00004474 | |||||
| WBPaper00030894 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 09 May 2008 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and cholesterol binding activity. Predicted to be involved in nucleosome assembly. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in appendiceal neoplasm; hepatoblastoma; and pancreatic cancer. Is an ortholog of human NAP1L1 (nucleosome assembly protein 1 like 1); NAP1L2 (nucleosome assembly protein 1 like 2); and NAP1L4 (nucleosome assembly protein 1 like 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:687 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7637) | ||||
| DOID:11240 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7637) | ||||||
| DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7637) | ||||||
| Molecular_info | Corresponding_CDS | D2096.8 | |||||||
| Corresponding_transcript | D2096.8.1 | ||||||||
| Other_sequence (138) | |||||||||
| Associated_feature | WBsf651995 | ||||||||
| WBsf977190 | |||||||||
| WBsf977191 | |||||||||
| WBsf230415 | |||||||||
| WBsf230416 | |||||||||
| WBsf230417 | |||||||||
| Experimental_info | RNAi_result (20) | ||||||||
| Expr_pattern | Expr1011979 | ||||||||
| Expr1037338 | |||||||||
| Expr1147527 | |||||||||
| Expr2013855 | |||||||||
| Expr2032095 | |||||||||
| Drives_construct | WBCnstr00017109 | ||||||||
| WBCnstr00027587 | |||||||||
| Construct_product | WBCnstr00017087 | ||||||||
| WBCnstr00017110 | |||||||||
| WBCnstr00027587 | |||||||||
| Antibody | WBAntibody00001278 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (149) | |||||||||
| Interaction (327) | |||||||||
| Map_info | Map | IV | Position | 3.7337 | Error | 0.004255 | |||
| Positive | Positive_clone | D2096 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
