WormBase Tree Display for Gene: WBGene00017012
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WBGene00017012 | SMap | S_parent | Sequence | D1009 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | acs | ||||||
Allele (144) | |||||||
Strain | WBStrain00004763 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00001951 | ||||||
00001952 | |||||||
00001953 | |||||||
00001954 | |||||||
00001955 | |||||||
00001956 | |||||||
00001957 | |||||||
00062816 | |||||||
Ortholog (44) | |||||||
Paralog (17) | |||||||
Structured_description | Concise_description | acs-22 encodes a protein homologous to the mammalian FATP1 and FATP4 fatty acid transport proteins (FATP)/very long chain fatty acid acyl-CoA synthetases; acs-22 functions redundantly with acs-20 to regulate formation of the cuticle surface barrier that prevents penetration of small molecules; acs-22 may affect cuticle development via its role in incorporation of very long chain fatty acids, but not other fatty acids, into sphingomyelin; an acs-22::gfp promoter fusion is expressed strongly in the intestine, with weaker expression seen in the pharynx, head neurons, and hypodermis. | Paper_evidence | WBPaper00035868 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 03 Feb 2010 00:00:00 | ||||||
Automated_description | Predicted to enable long-chain fatty acid transporter activity and long-chain fatty acid-CoA ligase activity. Predicted to be involved in triglyceride homeostasis. Located in endoplasmic reticulum. Expressed in head neurons; hypodermis; and pharynx. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human SLC27A1 (solute carrier family 27 member 1) and SLC27A4 (solute carrier family 27 member 4). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:9970 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10998) | ||
Molecular_info | Corresponding_CDS | D1009.1a | |||||
D1009.1c | |||||||
D1009.1d | |||||||
Corresponding_CDS_history | D1009.1b:wp271 | ||||||
Corresponding_transcript | D1009.1a.1 | ||||||
D1009.1c.1 | |||||||
D1009.1d.1 | |||||||
Other_sequence (52) | |||||||
Associated_feature (16) | |||||||
Experimental_info (7) | |||||||
Map_info | Map | X | Position | 0.449566 | Error | 0.000197 | |
Positive | Positive_clone | D1009 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (15) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |