WormBase Tree Display for Gene: WBGene00016990
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| WBGene00016990 | SMap | S_parent | Sequence | CD4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | vps-37 | Person_evidence | WBPerson3188 | |||||
| Sequence_name | CD4.4 | ||||||||
| Molecular_name | CD4.4 | ||||||||
| CD4.4.1 | |||||||||
| CE16952 | |||||||||
| Other_name | CELE_CD4.4 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | vps-37 | ||||||||
| DB_info | Database | AceView | gene | 5G71 | |||||
| WormQTL | gene | WBGene00016990 | |||||||
| WormFlux | gene | WBGene00016990 | |||||||
| NDB | locus_tag | CELE_CD4.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00016990|UniProtKB=O44158 | |||||||
| family | PTHR13678 | ||||||||
| NCBI | gene | 178944 | |||||||
| RefSeq | protein | NM_072073.5 | |||||||
| TREEFAM | TREEFAM_ID | TF321840 | |||||||
| TrEMBL | UniProtAcc | O44158 | |||||||
| UniProt_GCRP | UniProtAcc | O44158 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 10 Sep 2007 09:52:01 | WBPerson2970 | Name_change | CGC_name | vps-37 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | vps | ||||||||
| Allele (15) | |||||||||
| Strain | WBStrain00002948 | ||||||||
| WBStrain00036336 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Contained_in_operon | CEOP5076 | ||||||||
| Ortholog (44) | |||||||||
| Structured_description | Concise_description | vps-37 encodes the C. elegans ortholog of Saccharomyces cerevisiae Srn2p/Vps37p, a member of the endosomal sorting ESCRT-I complex that functions in endosomal sorting of mono-ubiquitinated membrane proteins; in C. elegans, VPS-37 is an essential component of the ESCRT-I complex (other members include VPS-28, MVB-12, and TSG-101) that affects the rate at which cell surface receptors are degraded and hence, the rate at which their activity is downregulated; a VPS-37::GFP fusion protein localizes to the cytosol and to endosomal membranes. | Paper_evidence | WBPaper00031035 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 09 Jul 2010 00:00:00 | ||||||||
| Automated_description | Involved in receptor catabolic process. Located in cytosol and endosome membrane. Part of ESCRT I complex. Expressed in head and tail. Is an ortholog of human VPS37B (VPS37B subunit of ESCRT-I). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info (4) | |||||||||
| Experimental_info | RNAi_result (60) | ||||||||
| Expr_pattern | Expr5605 | ||||||||
| Expr1018249 | |||||||||
| Expr1037296 | |||||||||
| Expr1147284 | |||||||||
| Expr2018028 | |||||||||
| Expr2036165 | |||||||||
| Drives_construct | WBCnstr00003454 | ||||||||
| WBCnstr00027652 | |||||||||
| Construct_product | WBCnstr00000920 | ||||||||
| WBCnstr00027652 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (105) | |||||||||
| Interaction (36) | |||||||||
| Map_info | Map | V | Position | -1.37551 | Error | 0.00596 | |||
| Positive | Positive_clone | CD4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (10) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
