WormBase Tree Display for Gene: WBGene00016192
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WBGene00016192 | SMap | S_parent | Sequence | C28H8 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | bcl-7 | Person_evidence | WBPerson426 | |||||
Sequence_name | C28H8.1 | ||||||||
Molecular_name | C28H8.1 | ||||||||
C28H8.1.1 | |||||||||
CE01820 | |||||||||
Other_name | CELE_C28H8.1 | Accession_evidence | NDB | BX284603 | |||||
Public_name | bcl-7 | ||||||||
DB_info | Database | AceView | gene | 3H17 | |||||
WormQTL | gene | WBGene00016192 | |||||||
WormFlux | gene | WBGene00016192 | |||||||
NDB | locus_tag | CELE_C28H8.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00016192|UniProtKB=Q09242 | |||||||
family | PTHR12767 | ||||||||
NCBI | gene | 175838 | |||||||
RefSeq | protein | NM_065886.6 | |||||||
SwissProt | UniProtAcc | Q09242 | |||||||
TREEFAM | TREEFAM_ID | TF317441 | |||||||
UniProt_GCRP | UniProtAcc | Q09242 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:57 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 20 May 2014 11:44:19 | WBPerson2970 | Name_change | CGC_name | bcl-7 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | bcl | ||||||||
Allele (15) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00053020 | ||||||||
00053021 | |||||||||
00053022 | |||||||||
00053023 | |||||||||
00053024 | |||||||||
Ortholog (43) | |||||||||
Structured_description | Concise_description | bcl-7 encodes the sole C. elegans member of the BCL7 family of proteins that contains human proteins, namely BCL7A and BCL7B, that are associated with malignant diseases; bcl-7 activity is required for proper terminal seam cell differentiation as well as for normal development of the distal tip cells of the somatic gonad and germ line; in controlling cell development and differentiation, bcl-7 interacts with the Wnt signaling pathway, regulating the asymmetric localization of WRM-1, and hence POP-1, in asymmetric cell divisions; bcl-7 may also function to regulate apoptosis, as loss of bcl-7 activity results in increased expression of ced-9; a BCL-7::GFP reporter is expressed ubiquitously and localized to nuclei; mammalian BCL7 family members are members of Swi/Snf transcriptional regulatory complexes. | Paper_evidence | WBPaper00046304 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson1823 | |||||||||
WBPerson567 | |||||||||
Date_last_updated | 20 May 2014 00:00:00 | ||||||||
Automated_description | Predicted to be involved in Wnt signaling pathway; apoptotic process; and cell differentiation. Predicted to be located in nucleus. Expressed in distal tip cell; germ cell; and gonadal sheath cell. Is an ortholog of human BCL7A (BAF chromatin remodeling complex subunit BCL7A). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C28H8.1 | |||||||
Corresponding_transcript | C28H8.1.1 | ||||||||
Other_sequence | Acan_isotig14735 | ||||||||
Oden_isotig13379 | |||||||||
CBC13479_1 | |||||||||
Tcir_isotig09201 | |||||||||
CJC05531_1 | |||||||||
Dviv_isotig33085 | |||||||||
Tcol_contig20712 | |||||||||
Oden_isotig13380 | |||||||||
JI180958.1 | |||||||||
Associated_feature | WBsf645222 | ||||||||
WBsf645223 | |||||||||
WBsf225029 | |||||||||
Experimental_info | RNAi_result | WBRNAi00061740 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00114621 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00029301 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00011309 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00005962 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076175 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00041425 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr12126 | ||||||||
Expr1015868 | |||||||||
Expr1036929 | |||||||||
Expr1145455 | |||||||||
Expr2009584 | |||||||||
Expr2027821 | |||||||||
Drives_construct (4) | |||||||||
Construct_product (4) | |||||||||
Microarray_results (21) | |||||||||
Expression_cluster (121) | |||||||||
Interaction (67) | |||||||||
Map_info | Map | III | Position | -1.43385 | |||||
Positive | Positive_clone | C28H8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00032961 | ||||||||
WBPaper00038491 | |||||||||
WBPaper00046304 | |||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |