WormBase Tree Display for Gene: WBGene00016144
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| WBGene00016144 | SMap | S_parent | Sequence | C26E6 | |||
|---|---|---|---|---|---|---|---|
| Identity (6) | |||||||
| Gene_info | Biotype | SO:0001217 | |||||
| Gene_class | mmab | ||||||
| Allele (18) | |||||||
| RNASeq_FPKM (74) | |||||||
| GO_annotation | 00060522 | ||||||
| 00060523 | |||||||
| 00060524 | |||||||
| 00060525 | |||||||
| 00060526 | |||||||
| 00060527 | |||||||
| Contained_in_operon | CEOP3240 | ||||||
| Ortholog (32) | |||||||
| Structured_description | Concise_description | mmab-1 encodes an ortholog of human co(I)balamin adenosyltransferase (MMAB); mmab-1 deletion mutants incorporate abnormally low levels of 1-[(14)C]-propionate into proteins; mmab-1 mutants and mmab-1(RNAi) animals excrete abnormally high levels of methylmalonic acid into their culture medium when challenged with propionic acid; these data are consistent with the hypothesis that MMAB-1 participates in the conversion of propionyl-CoA to succinyl-CoA. | Paper_evidence | WBPaper00027754 | |||
| Curator_confirmed | WBPerson567 | ||||||
| Date_last_updated | 02 Oct 2006 00:00:00 | ||||||
| Automated_description | Predicted to enable corrinoid adenosyltransferase activity. Used to study methylmalonic acidemia. Human ortholog(s) of this gene implicated in methylmalonic acidemia cblB type. Is an ortholog of human MMAB (metabolism of cobalamin associated B). | Paper_evidence | WBPaper00065943 | ||||
| Curator_confirmed | WBPerson324 | ||||||
| WBPerson37462 | |||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
| Disease_info (3) | |||||||
| Models_disease_in_annotation | WBDOannot00000285 | ||||||
| Molecular_info | Corresponding_CDS | C26E6.11 | |||||
| Corresponding_CDS_history | C26E6.11:wp152 | ||||||
| Corresponding_transcript | C26E6.11.1 | ||||||
| C26E6.11.2 | |||||||
| Other_sequence (31) | |||||||
| Associated_feature | WBsf651018 | ||||||
| WBsf666834 | |||||||
| WBsf666835 | |||||||
| WBsf666836 | |||||||
| WBsf666837 | |||||||
| WBsf226609 | |||||||
| WBsf226610 | |||||||
| Experimental_info | RNAi_result | WBRNAi00067760 | Inferred_automatically | RNAi_primary | |||
| WBRNAi00076161 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00011212 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00002187 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00078225 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00005233 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00007907 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00041267 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr1020305 | ||||||
| Expr1036905 | |||||||
| Expr1145309 | |||||||
| Expr2013625 | |||||||
| Expr2031859 | |||||||
| Drives_construct | WBCnstr00028295 | ||||||
| Construct_product | WBCnstr00028295 | ||||||
| Microarray_results (20) | |||||||
| Expression_cluster (96) | |||||||
| Interaction | WBInteraction000007214 | ||||||
| WBInteraction000173906 | |||||||
| WBInteraction000552627 | |||||||
| WBInteraction000553755 | |||||||
| Map_info | Map | III | Position | -2.35895 | Error | 0.002868 | |
| Positive | Positive_clone | C26E6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
| Pseudo_map_position | |||||||
| Reference | WBPaper00027754 | ||||||
| WBPaper00038491 | |||||||
| WBPaper00045654 | |||||||
| WBPaper00049923 | |||||||
| WBPaper00055090 | |||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
| Method | Gene |
