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WormBase Tree Display for Gene: WBGene00015971

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Name Class

WBGene00015971SMapS_parentSequenceC18E3
IdentityVersion2
NameCGC_nameswsn-2.2Person_evidenceWBPerson407
WBPerson552
Sequence_nameC18E3.2
Molecular_nameC18E3.2
C18E3.2.1
CE30249
Other_nameCELE_C18E3.2Accession_evidenceNDBBX284601
Public_nameswsn-2.2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
211 Feb 2011 15:09:46WBPerson2970Name_changeCGC_nameswsn-2.2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classswsn
Allele (31)
StrainWBStrain00029672
WBStrain00031318
WBStrain00037543
RNASeq_FPKM (74)
GO_annotation (16)
Contained_in_operonCEOP1946
Ortholog (44)
Paralog (4)
Structured_descriptionConcise_descriptionswsn-2.2 encodes a homolog of Swp73/BAF60, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; swsn-2.2 is probably required during mitosis of the T cells for asymmetric cell division.Paper_evidenceWBPaper00004350
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated01 Aug 2011 00:00:00
Automated_descriptionPredicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in condensed chromosome; nuclear envelope; and nucleoplasm. Expressed in several structures, including HSNL and HSNR. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 11. Is an ortholog of human SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1); SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2); and SMARCD3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:1574Homo sapiensPaper_evidenceWBPaper00046494
Curator_confirmedWBPerson324
Date_last_updated20 May 2019 00:00:00
Potential_modelEFO:MONDO:0009506Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11107)
DOID:0112372Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11106)
Models_disease_assertedWBDOannot00000665
Molecular_infoCorresponding_CDSC18E3.2
Corresponding_transcriptC18E3.2.1
Other_sequence (12)
Associated_featureWBsf643191
WBsf643192
WBsf656176
WBsf983356
WBsf217501
Experimental_infoRNAi_resultWBRNAi00007940Inferred_automaticallyRNAi_primary
WBRNAi00040936Inferred_automaticallyRNAi_primary
WBRNAi00061241Inferred_automaticallyRNAi_primary
WBRNAi00093893Inferred_automaticallyRNAi_primary
WBRNAi00069103Inferred_automaticallyRNAi_primary
WBRNAi00016521Inferred_automaticallyRNAi_primary
WBRNAi00061240Inferred_automaticallyRNAi_primary
WBRNAi00093974Inferred_automaticallyRNAi_primary
WBRNAi00093943Inferred_automaticallyRNAi_primary
Expr_patternExpr16204
Expr16205
Expr1016633
Expr1036825
Expr1144983
Expr2017157
Expr2035293
Drives_constructWBCnstr00017369
WBCnstr00028413
WBCnstr00042800
Construct_productWBCnstr00028413
WBCnstr00042800
Regulate_expr_clusterWBPaper00049018:swsn-2.2(RNAi)_downregulated
WBPaper00049018:swsn-2.2(RNAi)_upregulated
WBPaper00049018:SWSN-2.2_interacting
AntibodyWBAntibody00002683
Microarray_results (24)
Expression_cluster (135)
Interaction (345)
Map_infoMapIPosition-1.58056Error0.006827
PositivePositive_cloneC18E3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (8)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene