WormBase Tree Display for Gene: WBGene00015646
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WBGene00015646 | SMap | S_parent | Sequence | C09E8 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | mlt-10 | Person_evidence | WBPerson545 | |||
WBPerson3379 | |||||||
Sequence_name | C09E8.3 | ||||||
Molecular_name | C09E8.3 | ||||||
C09E8.3.1 | |||||||
CE19349 | |||||||
Other_name | C09E8.a | Curator_confirmed | WBPerson1983 | ||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||
CELE_C09E8.3 | Accession_evidence | NDB | BX284602 | ||||
Public_name | mlt-10 | ||||||
DB_info | Database | AceView | gene | 2A841 | |||
WormQTL | gene | WBGene00015646 | |||||
WormFlux | gene | WBGene00015646 | |||||
NDB | locus_tag | CELE_C09E8.3 | |||||
Panther | gene | CAEEL|WormBase=WBGene00015646|UniProtKB=O76555 | |||||
family | PTHR21523 | ||||||
NCBI | gene | 173445 | |||||
RefSeq | protein | NM_061354.5 | |||||
TREEFAM | TREEFAM_ID | TF315329 | |||||
TrEMBL | UniProtAcc | O76555 | |||||
UniProt_GCRP | UniProtAcc | O76555 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | mlt | ||||||
Allele (107) | |||||||
Strain | WBStrain00007913 | ||||||
WBStrain00007925 | |||||||
WBStrain00007926 | |||||||
WBStrain00007927 | |||||||
WBStrain00032646 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00038482 | ||||||
00038483 | |||||||
00038484 | |||||||
00038485 | |||||||
Ortholog (39) | |||||||
Paralog (13) | |||||||
Structured_description | Concise_description | mlt-10 encodes a nematode-specific protein that contains a domain of unknown function, DUF644, and tandem proline- and hydroxy amino acid-rich repeats; mlt-10 is required for proper execution of the molting cycle, as well as a number of other processes including normal body shape, locomotion, and reproduction; MLT-10 is expressed transiently with each molting cycle in the hypodermis, except for the lateral seam cells, and in the pharyngeal myoepithelium; MLT-10 is secreted into the surrounding matrix and fluids during molting and also found in strands near the animal surface; mlt-10 expression in the hypodermis depends upon the nuclear hormone receptors NHR-23 and NHR-25; MLT-10 contains thirteen paralogs in the C. elegans genome that, along with MLT-10, are all members of a large family of conserved nematode proteins. | Paper_evidence | WBPaper00036066 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 26 Mar 2010 00:00:00 | ||||||
Automated_description | Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and epidermis development. Located in extracellular space. Expressed in hypodermal cell and pharyngeal epithelial cell. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C09E8.3 | |||||
Corresponding_transcript | C09E8.3.1 | ||||||
Other_sequence | EX547584.1 | ||||||
ACC41112_1 | |||||||
SSC03996_1 | |||||||
CBC13394_1 | |||||||
JI468824.1 | |||||||
BXC01140_1 | |||||||
Associated_feature | WBsf643913 | ||||||
WBsf717623 | |||||||
WBsf717624 | |||||||
WBsf986435 | |||||||
WBsf220766 | |||||||
WBsf220767 | |||||||
Experimental_info | RNAi_result | WBRNAi00010520 | Inferred_automatically | RNAi_primary | |||
WBRNAi00040201 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00028724 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00098168 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Chronogram1648 | ||||||
Expr3696 | |||||||
Expr9014 | |||||||
Expr9015 | |||||||
Expr1022256 | |||||||
Expr1036700 | |||||||
Expr1144271 | |||||||
Expr2013604 | |||||||
Expr2031837 | |||||||
Drives_construct | WBCnstr00000978 | ||||||
WBCnstr00006118 | |||||||
WBCnstr00006119 | |||||||
WBCnstr00006887 | |||||||
WBCnstr00011607 | |||||||
WBCnstr00013673 | |||||||
WBCnstr00028689 | |||||||
Construct_product (5) | |||||||
Microarray_results (22) | |||||||
Expression_cluster (256) | |||||||
Interaction (36) | |||||||
Map_info | Map | II | Position | -15.5955 | Error | 0.000175 | |
Positive | Positive_clone | C09E8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (13) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |