WormBase Tree Display for Gene: WBGene00015646
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WBGene00015646 | SMap | S_parent | Sequence | C09E8 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | mlt-10 | Person_evidence | WBPerson545 | |||||
WBPerson3379 | |||||||||
Sequence_name | C09E8.3 | ||||||||
Molecular_name | C09E8.3 | ||||||||
C09E8.3.1 | |||||||||
CE19349 | |||||||||
Other_name | C09E8.a | Curator_confirmed | WBPerson1983 | ||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
CELE_C09E8.3 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | mlt-10 | ||||||||
DB_info | Database | AceView | gene | 2A841 | |||||
WormQTL | gene | WBGene00015646 | |||||||
WormFlux | gene | WBGene00015646 | |||||||
NDB | locus_tag | CELE_C09E8.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00015646|UniProtKB=O76555 | |||||||
family | PTHR21523 | ||||||||
NCBI | gene | 173445 | |||||||
RefSeq | protein | NM_061354.5 | |||||||
TREEFAM | TREEFAM_ID | TF315329 | |||||||
TrEMBL | UniProtAcc | O76555 | |||||||
UniProt_GCRP | UniProtAcc | O76555 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 28 Jul 2005 14:21:20 | WBPerson2970 | Name_change | CGC_name | mlt-10 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | mlt | ||||||||
Allele (107) | |||||||||
Strain | WBStrain00007913 | ||||||||
WBStrain00007925 | |||||||||
WBStrain00007926 | |||||||||
WBStrain00007927 | |||||||||
WBStrain00032646 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (4) | |||||||||
Ortholog (39) | |||||||||
Paralog (13) | |||||||||
Structured_description | Concise_description | mlt-10 encodes a nematode-specific protein that contains a domain of unknown function, DUF644, and tandem proline- and hydroxy amino acid-rich repeats; mlt-10 is required for proper execution of the molting cycle, as well as a number of other processes including normal body shape, locomotion, and reproduction; MLT-10 is expressed transiently with each molting cycle in the hypodermis, except for the lateral seam cells, and in the pharyngeal myoepithelium; MLT-10 is secreted into the surrounding matrix and fluids during molting and also found in strands near the animal surface; mlt-10 expression in the hypodermis depends upon the nuclear hormone receptors NHR-23 and NHR-25; MLT-10 contains thirteen paralogs in the C. elegans genome that, along with MLT-10, are all members of a large family of conserved nematode proteins. | Paper_evidence | WBPaper00036066 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 26 Mar 2010 00:00:00 | ||||||||
Automated_description | Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and epidermis development. Located in extracellular space. Expressed in hypodermal cell and pharyngeal epithelial cell. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C09E8.3 | |||||||
Corresponding_transcript | C09E8.3.1 | ||||||||
Other_sequence | EX547584.1 | ||||||||
ACC41112_1 | |||||||||
SSC03996_1 | |||||||||
CBC13394_1 | |||||||||
JI468824.1 | |||||||||
BXC01140_1 | |||||||||
Associated_feature | WBsf643913 | ||||||||
WBsf717623 | |||||||||
WBsf717624 | |||||||||
WBsf986435 | |||||||||
WBsf220766 | |||||||||
WBsf220767 | |||||||||
Experimental_info | RNAi_result | WBRNAi00010520 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00040201 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00028724 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00098168 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Chronogram1648 | ||||||||
Expr3696 | |||||||||
Expr9014 | |||||||||
Expr9015 | |||||||||
Expr1022256 | |||||||||
Expr1036700 | |||||||||
Expr1144271 | |||||||||
Expr2013604 | |||||||||
Expr2031837 | |||||||||
Drives_construct | WBCnstr00000978 | ||||||||
WBCnstr00006118 | |||||||||
WBCnstr00006119 | |||||||||
WBCnstr00006887 | |||||||||
WBCnstr00011607 | |||||||||
WBCnstr00013673 | |||||||||
WBCnstr00028689 | |||||||||
Construct_product (5) | |||||||||
Microarray_results (22) | |||||||||
Expression_cluster (256) | |||||||||
Interaction (36) | |||||||||
Map_info | Map | II | Position | -15.5955 | Error | 0.000175 | |||
Positive | Positive_clone | C09E8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (13) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |