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WormBase Tree Display for Gene: WBGene00015406

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Name Class

WBGene00015406SMapS_parentSequenceC03H5
IdentityVersion1
NameSequence_nameC03H5.4
Molecular_nameC03H5.4a
C03H5.4a.1
CE07897
C03H5.4b
Other_nameCELE_C03H5.4Accession_evidenceNDBBX284602
Public_nameC03H5.4
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (16)
StrainWBStrain00055361
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (23)
ParalogWBGene00007419Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00045002Caenorhabditis elegansFrom_analysismodENCODE_Pseudogenes
WBGene00044468Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionC03H5.4 encodes a secreted phospholipase A2; based on similarity to mammalian enzymes, the product of C03H5.4 is predicted to function in phospholipid hydrolysis during fat digestion and/or host response to bacterial infection.Paper_evidenceWBPaper00032311
Curator_confirmedWBPerson1843
Date_last_updated11 Nov 2008 00:00:00
Automated_descriptionPredicted to enable calcium ion binding activity and phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion; lipid catabolic process; and phospholipid metabolic process. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including adult respiratory distress syndrome; cholecystolithiasis; and familial benign fleck retina. Is an ortholog of human PLA2G2A (phospholipase A2 group IIA); PLA2G2E (phospholipase A2 group IIE); and PLA2G5 (phospholipase A2 group V).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9256Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9031)
DOID:0111677Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9038)
DOID:11151Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9031)
DOID:8534Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9031)
DOID:1596Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9031)
DOID:11394Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9031)
DOID:526Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9031)
DOID:11204Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9031)
Molecular_infoCorresponding_CDSC03H5.4a
Corresponding_CDS_historyC03H5.4:wp221
Corresponding_transcriptC03H5.4b
C03H5.4a.1
Other_sequence (14)
Associated_featureWBsf986393
WBsf986394
WBsf986395
WBsf1011381
WBsf1011382
WBsf1011383
Experimental_infoRNAi_resultWBRNAi00102654Inferred_automaticallyRNAi_primary
WBRNAi00039561Inferred_automaticallyRNAi_primary
WBRNAi00102883Inferred_automaticallyRNAi_primary
WBRNAi00010085Inferred_automaticallyRNAi_primary
WBRNAi00028406Inferred_automaticallyRNAi_primary
Expr_patternExpr1018059
Expr1143663
Expr2000382
Expr2018605
Microarray_results (18)
Expression_cluster (31)
Interaction (45)
Map_infoPositivePositive_cloneC03H5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII-15.6165
ReferenceWBPaper00026800
WBPaper00038491
WBPaper00042257
WBPaper00055090
MethodGene