WormBase Tree Display for Gene: WBGene00015125
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| WBGene00015125 | SMap | S_parent | Sequence | B0303 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | hadb-1 | Person_evidence | WBPerson6609 | |||||
| WBPerson1816 | |||||||||
| Sequence_name | B0303.3 | ||||||||
| Molecular_name | B0303.3 | ||||||||
| B0303.3.1 | |||||||||
| CE00561 | |||||||||
| B0303.3.2 | |||||||||
| Other_name | CELE_B0303.3 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | hadb-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 05 May 2023 12:43:53 | WBPerson51134 | Name_change | CGC_name | hadb-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hadb | ||||||||
| Allele (33) | |||||||||
| Strain | WBStrain00002333 | ||||||||
| WBStrain00002408 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (45) | |||||||||
| Paralog | WBGene00002183 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00009952 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00020166 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00013284 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | B0303.3 is orthologous to the human gene 3-KETOACYL-COA THIOLASE BETA-SUBUNIT OF TRIFUNCTIONAL PROTEIN (HADHB; OMIM:143450), which when mutated leads to disease. | Curator_confirmed | WBPerson1823 | |||||
| WBPerson567 | |||||||||
| Date_last_updated | 06 Aug 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable acetyl-CoA C-acyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Located in mitochondrion. Expressed in tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; mitochondrial metabolism disease; and mitochondrial trifunctional protein deficiency. Is an ortholog of human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4803) | ||||
| DOID:700 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4803) | ||||||
| DOID:0111277 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4803) | ||||||
| Molecular_info | Corresponding_CDS | B0303.3 | |||||||
| Corresponding_transcript | B0303.3.1 | ||||||||
| B0303.3.2 | |||||||||
| Other_sequence (104) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00038903 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00102851 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00102624 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002564 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00028075 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00038902 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1688 | ||||||||
| Expr5045 | |||||||||
| Expr5046 | |||||||||
| Expr1010778 | |||||||||
| Expr1036463 | |||||||||
| Expr1143085 | |||||||||
| Expr2000130 | |||||||||
| Expr2018348 | |||||||||
| Drives_construct | WBCnstr00003002 | ||||||||
| WBCnstr00004497 | |||||||||
| WBCnstr00029067 | |||||||||
| Construct_product | WBCnstr00029067 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (118) | |||||||||
| Interaction (72) | |||||||||
| Map_info | Map | III | Position | -0.100936 | |||||
| Positive | Positive_clone | B0303 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00026800 | ||||||||
| WBPaper00029292 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00042257 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
