WormBase Tree Display for Gene: WBGene00013808
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| WBGene00013808 | SMap | S_parent | Sequence | Y116A8C | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | sfa-1 | Person_evidence | WBPerson2495 | |||||
| WBPerson268 | |||||||||
| Sequence_name | Y116A8C.32 | ||||||||
| Molecular_name | Y116A8C.32a | ||||||||
| Y116A8C.32a.1 | |||||||||
| CE28108 | |||||||||
| Y116A8C.32b | |||||||||
| Other_name | sf1 | Accession_evidence | EMBL | AJ243905 | |||||
| CELE_Y116A8C.32 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | sfa-1 | ||||||||
| DB_info | Database | AceView | gene | 4S48 | |||||
| WormQTL | gene | WBGene00013808 | |||||||
| WormFlux | gene | WBGene00013808 | |||||||
| NDB | locus_tag | CELE_Y116A8C.32 | |||||||
| Panther | gene | CAEEL|EnsemblGenome=WBGene00013808|UniProtKB=G5EF97 | |||||||
| family | PTHR11208 | ||||||||
| NCBI | gene | 178486 | |||||||
| RefSeq | protein | NM_070632.7 | |||||||
| NR_132466.1 | |||||||||
| TrEMBL | UniProtAcc | G5EF97 | |||||||
| UniProt_GCRP | UniProtAcc | G5EF97 | |||||||
| RNAcentral | URSid | URS000085AC17 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 01 Sep 2006 10:20:17 | WBPerson2970 | Name_change | Other_name | sf1 | ||||
| 3 | 04 Jun 2007 15:54:19 | WBPerson2970 | Name_change | CGC_name | sfa-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sfa | ||||||||
| Allele (177) | |||||||||
| Strain | WBStrain00027479 | ||||||||
| WBStrain00027594 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Contained_in_operon | CEOP4596 | ||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00001595 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00006423 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00010046 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00013325 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00017098 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00022101 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00044674 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00019509 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00304811 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | sfa-1 encodes an ortholog of splicing factor SF1, which enables 3' splice site recognition by binding U2AF65 and the intron branch site during splicing complex formation; SFA-1 shares several domains with mammalian SF1 proteins (a U2AF65 binding domain, a hnRNP K homology domain, two RNA-binding zinc knuckles, and a proline-rich C-terminal domain), while also sharing a hydrophilic N-terminal domain (enriched for serine, arginine, lysine, and aspartate) with Drosophila but not mammalian SF1; SFA-1's N-terminal domain resembles RS domains in other splicing proteins; sfa-1 is required for embryonic viability, normally rapid growth, and proper body morphology. | Paper_evidence | WBPaper00003817 | |||||
| WBPaper00005654 | |||||||||
| Person_evidence | WBPerson71 | ||||||||
| Curator_confirmed | WBPerson13481 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 17 Nov 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable mRNA binding activity. Involved in alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human SF1 (splicing factor 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y116A8C.32a | |||||||
| Corresponding_CDS_history | Y116A8C.32:wp32 | ||||||||
| Corresponding_transcript | Y116A8C.32b | ||||||||
| Y116A8C.32a.1 | |||||||||
| Other_sequence (32) | |||||||||
| Associated_feature | WBsf668583 | ||||||||
| WBsf668584 | |||||||||
| WBsf668585 | |||||||||
| WBsf998973 | |||||||||
| WBsf1018947 | |||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Expr1019252 | ||||||||
| Expr1036183 | |||||||||
| Expr1158961 | |||||||||
| Expr2015786 | |||||||||
| Expr2034019 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (77) | |||||||||
| Interaction (33) | |||||||||
| Map_info | Map | IV | Position | 16.1569 | Error | 0.005785 | |||
| Positive | Positive_clone | Y116A8C | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (17) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
