WormBase Tree Display for Gene: WBGene00013000

WBGene00013000 SMap: S_parent: Sequence: Y48E1B
  Identity: Version: 2
    Name: CGC_name: ddl-2 Person_evidence: WBPerson1157
      Sequence_name: Y48E1B.1
      Molecular_name: Y48E1B.1
        Y48E1B.1.1
        CE14854
      Other_name: CELE_Y48E1B.1 Accession_evidence: NDB BX284602
      Public_name: ddl-2
    DB_info: Database: AceView gene 2N832
        WormQTL gene WBGene00013000
        WormFlux gene WBGene00013000
        NDB locus_tag CELE_Y48E1B.1
        Panther gene CAEEL|WormBase=WBGene00013000|UniProtKB=O18195
          family PTHR23331
        NCBI gene 190025
        RefSeq protein NM_064446.5
        SwissProt UniProtAcc O18195
        TREEFAM TREEFAM_ID TF318222
        UniProt_GCRP UniProtAcc O18195
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 31 Aug 2005 14:07:05 WBPerson2970 Name_change: CGC_name: ddl-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ddl
    Allele (238)
    Strain: WBStrain00033055
    RNASeq_FPKM (74)
    GO_annotation (21)
    Contained_in_operon: CEOP2616
    Ortholog (32)
    Structured_description: Concise_description: ddl-2 encodes a novel, proline-rich protein; loss of ddl-2 activity via RNAi results in a daf-16-dependent increase in lifespan and enhanced dauer formation, but not extended lifespan, of daf-2(e1370) mutant animals. Paper_evidence: WBPaper00026715
          Curator_confirmed: WBPerson1843
          Date_last_updated: 08 Jul 2008 00:00:00
      Automated_description: Predicted to enable alpha-tubulin binding activity and gamma-tubulin binding activity. Involved in cytoplasmic sequestering of protein and determination of adult lifespan. Predicted to be located in early endosome and recycling endosome. Predicted to be part of WASH complex. Expressed in neurons. Is an ortholog of human WASH2P (WASP family homolog 2, pseudogene) and WASHC1 (WASH complex subunit 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y48E1B.1
    Corresponding_transcript: Y48E1B.1.1
    Other_sequence (1072)
    Associated_feature: WBsf990452
  Experimental_info: RNAi_result (17)
    Expr_pattern: Expr9956
      Expr1026095
      Expr1035775
      Expr1160357
      Expr2010826
      Expr2029064
    Drives_construct: WBCnstr00009739
      WBCnstr00009803
      WBCnstr00009804
    Construct_product: WBCnstr00009739
      WBCnstr00009804
    Microarray_results (19)
    Expression_cluster (75)
    Interaction (44)
  Map_info: Map: II Position: 18.0054 Error: 0.069729
    Positive: Positive_clone: Y48E1B Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026715
    WBPaper00033827
    WBPaper00038491
    WBPaper00040689
    WBPaper00044673
    WBPaper00049198
    WBPaper00055090
    WBPaper00066328
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene