WormBase Tree Display for Gene: WBGene00012769
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WBGene00012769 | SMap | S_parent | Sequence | Y41E3 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | hrpu | |||||
Allele (205) | ||||||
RNASeq_FPKM (74) | ||||||
Contained_in_operon | CEOP4685 | |||||
Ortholog (39) | ||||||
Paralog | WBGene00017620 | Caenorhabditis elegans | From_analysis | Panther | ||
WormBase-Compara | ||||||
WBGene00008035 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
Structured_description | Automated_description | Enriched in several structures, including AVE; germ line; mechanosensory neurons; rectal epithelial cell; and rectum based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including aldicarb; rotenone; and Cry5B based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in colorectal cancer and developmental and epileptic encephalopathy 54. Human HNRNPU enables several functions, including ATP binding activity; basal RNA polymerase II transcription machinery binding activity; and nucleic acid binding activity. Is predicted to encode a protein with the following domains: B30.2/SPRY domain superfamily; SPRY domain; Concanavalin A-like lectin/glucanase domain superfamily; P-loop containing nucleoside triphosphate hydrolase; and AAA domain. Is an ortholog of human HNRNPU (heterogeneous nuclear ribonucleoprotein U) and HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U like 2). | Paper_evidence | WBPaper00065943 | ||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5048) | |
DOID:0080418 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5048) | |||
Molecular_info | Corresponding_CDS | Y41E3.11a | ||||
Y41E3.11b | ||||||
Y41E3.11c | ||||||
Y41E3.11d | ||||||
Corresponding_transcript | Y41E3.11e | |||||
Y41E3.11a.1 | ||||||
Y41E3.11a.2 | ||||||
Y41E3.11b.1 | ||||||
Y41E3.11c.1 | ||||||
Y41E3.11d.1 | ||||||
Other_sequence | PPC13226_1 | |||||
JO470638.1 | ||||||
Oden_isotig18713 | ||||||
CRC11320_1 | ||||||
JI475266.1 | ||||||
HG07867 | ||||||
HGC04318_1 | ||||||
Acan_isotig22626 | ||||||
JI164039.1 | ||||||
Associated_feature (13) | ||||||
Experimental_info | RNAi_result (22) | |||||
Expr_pattern | Expr1026223 | |||||
Expr1035651 | ||||||
Expr1159886 | ||||||
Expr2012604 | ||||||
Expr2030840 | ||||||
Microarray_results (28) | ||||||
Expression_cluster (121) | ||||||
Interaction (176) | ||||||
Map_info | Positive | Positive_clone | Y41E3 | Inferred_automatically | From sequence, transcript, pseudogene data | |
Interpolated_map_position | IV | 12.8204 | ||||
Reference | WBPaper00038491 | |||||
WBPaper00052934 | ||||||
WBPaper00055090 | ||||||
Method | Gene |