WormBase Tree Display for Gene: WBGene00012650
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| WBGene00012650 | SMap | S_parent | Sequence | Y39A1A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | orc-1 | Person_evidence | WBPerson195 | |||||
| Sequence_name | Y39A1A.12 | ||||||||
| Molecular_name | Y39A1A.12 | ||||||||
| Y39A1A.12.1 | |||||||||
| CE19131 | |||||||||
| Other_name | CELE_Y39A1A.12 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | orc-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 17 Jun 2011 16:06:01 | WBPerson2970 | Name_change | CGC_name | orc-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | orc | ||||||||
| Allele (45) | |||||||||
| Strain | WBStrain00005745 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00104077 | ||||||||
| 00104078 | |||||||||
| 00104079 | |||||||||
| 00104080 | |||||||||
| 00104081 | |||||||||
| 00104082 | |||||||||
| 00104083 | |||||||||
| 00104084 | |||||||||
| 00119687 | |||||||||
| 00119688 | |||||||||
| Contained_in_operon | CEOP3692 | ||||||||
| Ortholog (38) | |||||||||
| Paralog | WBGene00000382 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | Y39A1A.12 encodes a homolog of origin recognition complex 1, which is also a distant paralog of CDC-6; both Y39A1A.12 and CDC-6 encode homologs of the origin complex which, in yeast, controls the start of DNA replication; whether either Y39A1A.12 or CDC-6 are required for this function in C. elegans, individually or in parallel, is unknown. | Paper_evidence | WBPaper00013079 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA binding activity. Predicted to be involved in DNA replication initiation and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 1. Is an ortholog of human ORC1 (origin recognition complex subunit 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080512 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8487) | ||||
| Molecular_info | Corresponding_CDS | Y39A1A.12 | |||||||
| Corresponding_transcript | Y39A1A.12.1 | ||||||||
| Other_sequence | CRC09666_1 | ||||||||
| FC820332.1 | |||||||||
| Oden_isotig19249 | |||||||||
| CR01962 | |||||||||
| SRC07765_1 | |||||||||
| CBC05834_1 | |||||||||
| CJC00699_1 | |||||||||
| Hbac_isotig01464 | |||||||||
| CBC09470_1 | |||||||||
| CRC05891_1 | |||||||||
| Associated_feature | WBsf645573 | ||||||||
| WBsf658535 | |||||||||
| WBsf225742 | |||||||||
| WBsf225743 | |||||||||
| WBsf225744 | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern | Expr13394 | ||||||||
| Expr1019153 | |||||||||
| Expr1035590 | |||||||||
| Expr1159616 | |||||||||
| Expr2014633 | |||||||||
| Expr2032866 | |||||||||
| Construct_product | WBCnstr00009673 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (169) | |||||||||
| Interaction (154) | |||||||||
| Map_info | Map | III | Position | 4.21982 | Error | 0.030533 | |||
| Positive | Positive_clone | Y39A1A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00028564 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
