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WormBase Tree Display for Gene: WBGene00000382

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Name Class

WBGene00000382SMapS_parentSequenceC43E11
IdentityVersion1
NameCGC_namecdc-6
Sequence_nameC43E11.10
Molecular_nameC43E11.10
C43E11.10.1
CE08688
Other_nameCELE_C43E11.10Accession_evidenceNDBBX284601
Public_namecdc-6
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcdc
Allele (36)
StrainWBStrain00037796
RNASeq_FPKM (74)
GO_annotation (15)
Contained_in_operonCEOP1172
Ortholog (31)
ParalogWBGene00012650Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptioncdc-6 encodes a homolog of an origin complex component (CDC6) which in yeast controls the start of DNA replication, and also has a distant paralog (Y39A1A.12) within the C. elegans genome; CDC-6 is superficially dispensable for embryonic viability, perhaps because of redundancy with Y39A1A.12.Paper_evidenceWBPaper00013079
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in mitotic DNA replication checkpoint signaling. Located in condensed nuclear chromosome; cytoplasm; and nucleolus. Expressed in seam cell. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 5. Is an ortholog of human CDC6 (cell division cycle 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080516Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1744)
Molecular_infoCorresponding_CDSC43E11.10
Corresponding_transcriptC43E11.10.1
Other_sequence (19)
Associated_featureWBsf649089
WBsf664135
WBsf219260
Experimental_infoRNAi_result (20)
Expr_patternExpr4680
Expr4681
Expr9926
Expr1028747
Expr1030208
Expr1146367
Expr2009790
Expr2028030
Drives_constructWBCnstr00037581
Construct_productWBCnstr00000444
WBCnstr00000445
WBCnstr00000446
WBCnstr00000447
WBCnstr00007279
WBCnstr00009675
WBCnstr00012168
WBCnstr00015914
WBCnstr00037581
AntibodyWBAntibody00001255
Microarray_results (20)
Expression_cluster (111)
Interaction (118)
Map_infoMapIPosition-1.51655Error0.002838
PositivePositive_cloneC43E11Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00010683
WBPaper00010686
WBPaper00029399
WBPaper00033555
WBPaper00038491
WBPaper00040279
WBPaper00040645
WBPaper00045289
WBPaper00052102
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene