WormBase Tree Display for Gene: WBGene00012148
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WBGene00012148 | SMap | S_parent | Sequence | CHROMOSOME_II | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | inos | ||||||
Allele (39) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (11) | |||||||
Ortholog (36) | |||||||
Structured_description | Concise_description | inos-1 encodes the C. elegans myo-inositol-1-phosphate (MIP) synthase ortholog; by homology, the product of inos-1 is predicted to function in de novo inositol biosynthesis by catalyzing the conversion of glucose-6-phosphate to inositol-1-phosphate; loss of inos-1 activity via RNAi has been reported to result in low levels of embryonic lethality, larval lethality, slow growth, uncoordinated locomotion, and a substantial increase in fat content; loss of inos-1 activity also results in a slight increase in the variability of the defecation cycle length, although this increase is not statistically significant; in situ hybridization studies reveal that inos-1 mRNA is expressed faintly in the germline. | Paper_evidence | WBPaper00005654 | |||
WBPaper00005655 | |||||||
WBPaper00006395 | |||||||
WBPaper00025054 | |||||||
WBPaper00027758 | |||||||
WBPaper00031535 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 05 May 2011 00:00:00 | ||||||
Automated_description | Predicted to enable inositol-3-phosphate synthase activity. Predicted to be involved in inositol biosynthetic process. Predicted to be located in cytoplasm. Expressed in germ line. Is an ortholog of human ISYNA1 (inositol-3-phosphate synthase 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | VF13D12L.1 | |||||
Corresponding_transcript | VF13D12L.1.1 | ||||||
Other_sequence (81) | |||||||
Associated_feature | WBsf650614 | ||||||
WBsf650615 | |||||||
WBsf650616 | |||||||
WBsf666190 | |||||||
WBsf666191 | |||||||
WBsf989857 | |||||||
WBsf223984 | |||||||
Experimental_info | RNAi_result (8) | ||||||
Expr_pattern | Expr4091 | ||||||
Expr1023077 | |||||||
Expr1035373 | |||||||
Expr1158012 | |||||||
Expr2012744 | |||||||
Expr2030981 | |||||||
Drives_construct | WBCnstr00030104 | ||||||
Construct_product | WBCnstr00030104 | ||||||
Microarray_results (19) | |||||||
Expression_cluster (148) | |||||||
Interaction (76) | |||||||
Map_info | Map | II | Position | 3.99091 | Error | 0.005099 | |
Positive | Positive_clone | VF13D12L | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (4) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |