WormBase Tree Display for Gene: WBGene00011696
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WBGene00011696 | SMap | S_parent | Sequence | T10G3 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | eea-1 | Person_evidence | WBPerson217 | |||
Sequence_name | T10G3.5 | ||||||
Molecular_name | T10G3.5a | ||||||
T10G3.5a.1 | |||||||
CE31066 | |||||||
T10G3.5b | |||||||
CE37989 | |||||||
T10G3.5b.1 | |||||||
Other_name | CELE_T10G3.5 | Accession_evidence | NDB | BX284605 | |||
Public_name | eea-1 | ||||||
DB_info | Database | AceView | gene | 5N972 | |||
WormQTL | gene | WBGene00011696 | |||||
WormFlux | gene | WBGene00011696 | |||||
NDB | locus_tag | CELE_T10G3.5 | |||||
Panther | gene | CAEEL|WormBase=WBGene00011696|UniProtKB=G5ED80 | |||||
family | PTHR23164 | ||||||
NCBI | gene | 179832 | |||||
RefSeq | protein | NM_001028957.5 | |||||
NM_001028956.4 | |||||||
TREEFAM | TREEFAM_ID | TF329698 | |||||
TrEMBL | UniProtAcc | Q5FC45 | |||||
G5ED80 | |||||||
UniProt_GCRP | UniProtAcc | G5ED80 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | eea | ||||||
Allele (100) | |||||||
Strain | WBStrain00031782 | ||||||
WBStrain00036163 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00013516 | ||||||
00013517 | |||||||
00013518 | |||||||
00013519 | |||||||
00013520 | |||||||
00013521 | |||||||
00013522 | |||||||
00013523 | |||||||
00013524 | |||||||
00118935 | |||||||
Ortholog (34) | |||||||
Paralog | WBGene00007124 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | |||
Structured_description | Concise_description | eea-1 encodes a coiled-coil protein that is the C. elegans ortholog of early endosome antigen 1 (EEA1); eea-1 activity is required for wild-type levels of endocytosis; a fusion protein between EEA-1 FYVE domains and GFP binds endosomal/vacuolar membranes in wild-type worms but not in those lacking vps-34 activity, suggesting that, like its human ortholog, C. elegans EEA-1 binds phosphatidylinositol 3-phosphate (PtdIns 3-P) in vivo; EEA-1 reporter fusion proteins localize to early endosomes. | Paper_evidence | WBPaper00005216 | |||
WBPaper00025238 | |||||||
WBPaper00028279 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 07 Jan 2011 00:00:00 | ||||||
Automated_description | Enables phosphatidylinositol-3-phosphate binding activity. Involved in endocytosis. Located in early endosome and endocytic vesicle. Expressed in hypodermis and intestine. Is an ortholog of human EEA1 (early endosome antigen 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T10G3.5a | |||||
T10G3.5b | |||||||
Corresponding_CDS_history | T10G3.5:wp80 | ||||||
T10G3.5:wp138 | |||||||
Corresponding_transcript | T10G3.5a.1 | ||||||
T10G3.5b.1 | |||||||
Other_sequence (22) | |||||||
Associated_feature | WBsf653313 | ||||||
WBsf653314 | |||||||
WBsf669597 | |||||||
WBsf234817 | |||||||
Transcription_factor | WBTranscriptionFactor000915 | ||||||
Experimental_info | RNAi_result | WBRNAi00078222 | Inferred_automatically | RNAi_primary | |||
WBRNAi00018557 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00053068 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr11893 | ||||||
Expr1023427 | |||||||
Expr1035145 | |||||||
Expr1156676 | |||||||
Expr2011176 | |||||||
Expr2029412 | |||||||
Drives_construct | WBCnstr00001792 | ||||||
Construct_product (3) | |||||||
Antibody | WBAntibody00000923 | ||||||
WBAntibody00001088 | |||||||
WBAntibody00001323 | |||||||
WBAntibody00001956 | |||||||
Microarray_results (25) | |||||||
Expression_cluster (122) | |||||||
Interaction (35) | |||||||
Map_info | Map | V | Position | 5.35055 | Error | 0.000717 | |
Positive | Positive_clone | T10G3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (21) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |