WormBase Tree Display for Gene: WBGene00011696
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WBGene00011696 | SMap | S_parent | Sequence | T10G3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | eea-1 | Person_evidence | WBPerson217 | |||||
Sequence_name | T10G3.5 | ||||||||
Molecular_name | T10G3.5a | ||||||||
T10G3.5a.1 | |||||||||
CE31066 | |||||||||
T10G3.5b | |||||||||
CE37989 | |||||||||
T10G3.5b.1 | |||||||||
Other_name | CELE_T10G3.5 | Accession_evidence | NDB | BX284605 | |||||
Public_name | eea-1 | ||||||||
DB_info | Database | AceView | gene | 5N972 | |||||
WormQTL | gene | WBGene00011696 | |||||||
WormFlux | gene | WBGene00011696 | |||||||
NDB | locus_tag | CELE_T10G3.5 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00011696|UniProtKB=G5ED80 | |||||||
family | PTHR23164 | ||||||||
NCBI | gene | 179832 | |||||||
RefSeq | protein | NM_001028957.5 | |||||||
NM_001028956.4 | |||||||||
TREEFAM | TREEFAM_ID | TF329698 | |||||||
TrEMBL | UniProtAcc | Q5FC45 | |||||||
G5ED80 | |||||||||
UniProt_GCRP | UniProtAcc | G5ED80 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 04 Nov 2004 16:11:20 | WBPerson2970 | Name_change | CGC_name | eea-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | eea | ||||||||
Allele (100) | |||||||||
Strain | WBStrain00031782 | ||||||||
WBStrain00036163 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00013516 | ||||||||
00013517 | |||||||||
00013518 | |||||||||
00013519 | |||||||||
00013520 | |||||||||
00013521 | |||||||||
00013522 | |||||||||
00013523 | |||||||||
00013524 | |||||||||
00118935 | |||||||||
Ortholog (34) | |||||||||
Paralog | WBGene00007124 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | |||||
Structured_description | Concise_description | eea-1 encodes a coiled-coil protein that is the C. elegans ortholog of early endosome antigen 1 (EEA1); eea-1 activity is required for wild-type levels of endocytosis; a fusion protein between EEA-1 FYVE domains and GFP binds endosomal/vacuolar membranes in wild-type worms but not in those lacking vps-34 activity, suggesting that, like its human ortholog, C. elegans EEA-1 binds phosphatidylinositol 3-phosphate (PtdIns 3-P) in vivo; EEA-1 reporter fusion proteins localize to early endosomes. | Paper_evidence (3) | ||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 07 Jan 2011 00:00:00 | ||||||||
Automated_description | Enables phosphatidylinositol-3-phosphate binding activity. Involved in endocytosis. Located in early endosome and endocytic vesicle. Expressed in hypodermis and intestine. Is an ortholog of human EEA1 (early endosome antigen 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T10G3.5a | |||||||
T10G3.5b | |||||||||
Corresponding_CDS_history | T10G3.5:wp80 | ||||||||
T10G3.5:wp138 | |||||||||
Corresponding_transcript | T10G3.5a.1 | ||||||||
T10G3.5b.1 | |||||||||
Other_sequence (22) | |||||||||
Associated_feature (4) | |||||||||
Transcription_factor | WBTranscriptionFactor000915 | ||||||||
Experimental_info | RNAi_result | WBRNAi00078222 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00018557 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00053068 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr11893 | ||||||||
Expr1023427 | |||||||||
Expr1035145 | |||||||||
Expr1156676 | |||||||||
Expr2011176 | |||||||||
Expr2029412 | |||||||||
Drives_construct | WBCnstr00001792 | ||||||||
Construct_product | WBCnstr00001792 | ||||||||
WBCnstr00001798 | |||||||||
WBCnstr00009012 | |||||||||
Antibody | WBAntibody00000923 | ||||||||
WBAntibody00001088 | |||||||||
WBAntibody00001323 | |||||||||
WBAntibody00001956 | |||||||||
Microarray_results (25) | |||||||||
Expression_cluster (122) | |||||||||
Interaction (35) | |||||||||
Map_info | Map | V | Position | 5.35055 | Error | 0.000717 | |||
Positive | Positive_clone | T10G3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (21) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |