WormBase Tree Display for Gene: WBGene00011600
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| WBGene00011600 | SMap | S_parent | Sequence | T07G12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | zim-2 | Person_evidence | WBPerson136 | |||||
| Sequence_name | T07G12.10 | ||||||||
| Molecular_name | T07G12.10 | ||||||||
| T07G12.10.1 | |||||||||
| CE29521 | |||||||||
| T07G12.10.2 | |||||||||
| T07G12.10.3 | |||||||||
| Other_name | CELE_T07G12.10 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | zim-2 | ||||||||
| DB_info | Database | AceView | gene | 4L323 | |||||
| WormQTL | gene | WBGene00011600 | |||||||
| WormFlux | gene | WBGene00011600 | |||||||
| NDB | locus_tag | CELE_T07G12.10 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00011600|UniProtKB=O18067 | |||||||
| family | PTHR36945 | ||||||||
| NCBI | gene | 177948 | |||||||
| RefSeq | protein | NM_001383192.2 | |||||||
| TREEFAM | TREEFAM_ID | TF319120 | |||||||
| TrEMBL | UniProtAcc | O18067 | |||||||
| UniProt_GCRP | UniProtAcc | O18067 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 28 Jul 2005 14:00:57 | WBPerson2970 | Name_change | CGC_name | zim-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | zim | ||||||||
| Allele (48) | |||||||||
| Strain | WBStrain00004045 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00031359 | ||||||||
| 00031360 | |||||||||
| 00031361 | |||||||||
| Contained_in_operon | CEOP4384 | ||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00001867 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00011597 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00011601 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00015352 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | zim-2 encodes a protein with two C-terminal noncanonical C2H2zinc-fingers whose paralogs include HIM-8, ZIM-1, ZIM-3, and C02F5.12;ZIM-2 is specifically required for homolog pairing, synapsis, andsegregation of chromosome V during meiosis; zim-2(tm574) oocytes endingprophase have ~5 bivalents and ~2 univalents, the latter of which areconsistently chromosome V; zim-2 oocytes fail to begin chromosome Vpairing at the start of meiosis; ZIM-2 associates with the right end ofchromosome V, which may indicate an association with its pairing center;while the C-terminal region of ZIM-2 most closely resembles those of itsorthologs in other Caenorhabditis species, its N-terminal region insteadmost closely resembles those of its paralogs in C. elegans, indicatingcoevolving, species-specific functions; ZIM-2 foci, like HIM-8 foci,associate with the nuclear envelope during meiotic prophase; zim-2mutants also have some defective segregation of the X chromosome(yielding a Him phenotype), but this may be an indirect effect ofautosomal asynapsis. | Paper_evidence | WBPaper00026985 | |||||
| WBPaper00028860 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 22 Mar 2007 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in meiotic chromosome segregation. Located in condensed nuclear chromosome. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T07G12.10 | |||||||
| Corresponding_CDS_history | T07G12.10:wp56 | ||||||||
| Corresponding_transcript | T07G12.10.1 | ||||||||
| T07G12.10.2 | |||||||||
| T07G12.10.3 | |||||||||
| Other_sequence | CRC04924_1 | ||||||||
| CR03204 | |||||||||
| Transcription_factor | WBTranscriptionFactor001142 | ||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Expr4562 | ||||||||
| Expr1012792 | |||||||||
| Expr1035113 | |||||||||
| Expr1156390 | |||||||||
| Expr2018150 | |||||||||
| Expr2036287 | |||||||||
| Drives_construct | WBCnstr00030530 | ||||||||
| Construct_product | WBCnstr00030530 | ||||||||
| Antibody | WBAntibody00001189 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (121) | |||||||||
| SAGE_tag (15) | |||||||||
| Interaction (242) | |||||||||
| Map_info | Map | IV | Position | 4.63902 | |||||
| Positive | Positive_clone | T07G12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5330 | |||||||
| 5415 | |||||||||
| 5421 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (28) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
